Results 41 to 50 of about 180,185 (219)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Perennial changes and distribution of resources the main species of hunting animals of Russian

Аграрная наука Евро-Северо-Востока, 2016
The paper presents the assessment of the state in numbers, distribution on the territory and trends of the dynamics at the turn of XX-XXI centuries of the most economically important species of hunting resources in Russia.
V. V. Kolesnikov, V. N. Piminov, A. V. Ekonomov, M. S. Shevnina, D. S. Makarova, D. P. Strelnikov, A. A. Sinitsyin, D. V. Skumatov, E. S. Tuzharov, V. I. Mashkin, A. P. Pankratov, I. S. Kozlovskiy   +11 more
doaj  

Karakteristik dan keragaman input produksi usahatani lada putih (Muntok White Pepper) di provinsi Kepulauan Bangka Belitung

AGROMIX, 2019
White pepper is an annual plant which has a good prospect to be developed now and future. Kepulauan Bangka Belitung Province becomes the top white pepper producing province as well as the main exporter in Indonesia.
Yulia Yulia, Novyandra Ilham Bahtera, Herry Marta Saputra   +2 more
doaj   +1 more source

Obesity Subtypes and Longitudinal Trajectories of Function Over Seven Years of Follow‐Up: Data From the Multicenter Osteoarthritis Study

Arthritis Care &Research, EarlyView.
Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi, for the Multicenter Osteoarthritis Study Group   +7 more
wiley   +1 more source

Smart Pig Farms: Integration and Application of Digital Technologies in Pig Production

Agriculture
The prediction that the world population will reach almost 10 billion people by 2050 means an increase in pork production is required. Efforts to meet increased demand have made pig production one of the most technologically advanced branches of ...
Katarina Marić, Kristina Gvozdanović, Ivona Djurkin Kušec, Goran Kušec, Vladimir Margeta   +4 more
doaj   +1 more source

Heavy metal driven co-selection of antibiotic resistance in soil and water bodies impacted by agriculture and aquaculture

Frontiers in Microbiology, 2012
The use of antibiotic agents as growth promoters was banned in animal husbandry to prevent the selection and spread of antibiotic resistance. However, in addition to antibiotic agents, heavy metals used in animal farming and aquaculture might promote the
Claudia eSeiler, Thomas Ulrich Berendonk
doaj   +1 more source

Carboxylic‐Acid Functionalized Multiwalled Carbon Nanotube‐Alkane‐Based Resistive Temperature Sensor for Cold Chain Applications

Advanced Engineering Materials, EarlyView.
This study presents a reversible temperature sensor with high switching ratio, ∼103. The device is fabricated using PET‐ITO and carbon nanotube dispersions in alkane. Considering its application in cold chain logistics, a proof‐of‐concept with LED is showcased. Thus, a temperature drop below the threshold temperature (crystallization temperature of the
Sunil Kumar Behera, Philippe Marrec, A. Jorge Parola, Madalena Dionísio, Hugo Águas, Andreia F. M. Santos, Hamed Pourkheirollah, Donald Lupo, César A. T. Laia   +8 more
wiley   +1 more source

How sustainable is tuna aquaculture? A methodology to assess the sustainability of seafood production systems

Frontiers in Aquaculture
IntroductionConsidering the need to feed the increasing world population, it is essential to ensure that food production systems are sustainable. Aquaculture has been identified as a potential crucial source of sustainable food with its significant ...
Jordi Guillen, Frank Asche, Frank Asche, Natacha Carvalho, Jean-Noël Druon, Ignacio Llorente, Andrew Sciberras, Svjetlana Višnić Novaković, Ivana Vukov   +8 more
doaj   +1 more source

The Role of Governance in Agricultural Expansion and Intensification: a Global Study of Arable Agriculture

Ecology and Society, 2011
In this research we studied empirical relationships between agricultural production dynamics and six quantitative World Bank governance indicators for 173 countries between 1975 and 2007.
Menno Mandemaker, Martha Bakker, Jetse Stoorvogel   +2 more
doaj   +1 more source