Results 41 to 50 of about 603,250 (286)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Team 3: Using Data Farming to Develop and Evaluate IED Scenarios for PAX [PDF]

open access: yes, 2010
from Scythe : Proceedings and Bulletin of the International Data Farming Community, Issue 8 Workshop ...

core   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Scythe : Proceedings and Bulletin of the International Data Farming Community, Issue 15 Workshop 27 [PDF]

open access: yes, 2013
Proceedings and Bulletin of the International Data Farming Community, Issue 15, Workshop 27 Publication date: May ...
Horne, Gary, Meyer, Ted
core   +2 more sources

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Team 2: Using Data Farming to Examine Various Aspects of the Transformable Craft [PDF]

open access: yes, 2010
from Scythe : Proceedings and Bulletin of the International Data Farming Community, Issue 8 Workshop ...
Beery, Paul T.   +5 more
core   +2 more sources

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Team 3: Data Farming the Agent-Based ELICIT (abELICIT) Model [PDF]

open access: yes, 2010
from Scythe : Proceedings and Bulletin of the International Data Farming Community, Issue 9 Workshop 21ELICIT (Experimental Laboratory for the Investigation of Collaboration, Information-sharing and Trust) is a research and experimentation program ...
Upton, Stephen C.   +5 more
core   +2 more sources

Melanophilin Polymorphism of Exons 8 and 13 in Rabbits: Parent Breeds and Interbreed Cross Rodnik

open access: yesТехника и технология пищевых производств
New breeds of fur-bearing animals are multi-breed crosses. Selection requires new methods for genetic control. This article describes a new early-maturing and highly-productive crossbreed of rabbits called Rodnik obtained at the Afanasyev Research ...
Kosovsky Gleb   +6 more
doaj   +1 more source

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