Results 201 to 210 of about 24,275 (247)

Lactobacillus rhamnosus GG maintains gut microbiota stability and promotes intestinal adaptation via activated intestinal farnesoid X receptor signaling in short bowel syndrome. [PDF]

Commun Biol
Gui L, Duan X, Wang H, Xie H, Zhang R, Jiang W, Tang W.   +6 more
europepmc   +1 more source

Role of Obeticholic Acid, a Farnesoid X Receptor Agonist, in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. [PDF]

touchREV Endocrinol
Kamrul-Hasan A, Mondal S, Nagendra L, Sasikanth T, Ahammed A, Rahman S, Wickramarachchi A, Parajuli N, Khatiwada S, Dutta D.   +9 more
europepmc   +1 more source

On the Cholesterol Raising Effect of Coffee Diterpenes Cafestol and 16-O-Methylcafestol: Interaction with Farnesoid X Receptor. [PDF]

Int J Mol Sci
Guercia E, Berti F, De Zorzi R, Navarini L, Geremia S, Medagli B, De Conto M, Cassetta A, Forzato C.   +8 more
europepmc   +1 more source

Bidirectional interaction between farnesoid X Receptor and MicroRNAs

, 2016
openaire   +2 more sources

The Farnesoid X Receptor as a Master Regulator of Hepatotoxicity

International Journal of Molecular Sciences, 2022
The nuclear receptor farnesoid X receptor (FXR, NR1H4) is a bile acid (BA) sensor that links the enterohepatic circuit that regulates BA metabolism and elimination to systemic lipid homeostasis. Furthermore, FXR represents a real guardian of the hepatic function, preserving, in a multifactorial fashion, the integrity and function of hepatocytes from ...
Magdalena Rausch, Sophia L Samodelov, Michele Visentin   +2 more
exaly   +4 more sources

Some of the next articles are maybe not open access.

Related searches:

Identification of the expression of farnesoid X receptor in astrocytes

NeuroReport, 2021
Recently, we have identified a functional expression of farnesoid X receptor (FXR) in neurons in vitro and in vivo. However, whether the FXR is expressed in astrocytes remains unclear. In the present study, we addressed this issue by using an array of experimental methods such as immunofluorescence and western blot. Results showed that the FXR mRNA and
Haiyan, He, Zhuo, Chen, Dongjian, Chen, Xu, Lu, Chao, Huang, Jinliang, Chen   +5 more
openaire   +2 more sources

Role of farnesoid X receptor in cholestasis

Journal of Digestive Diseases, 2016
The nuclear receptor farnesoid X receptor (FXR) plays an important role in physiological bile acid synthesis, secretion and transport. Defects of FXR regulation in these processes can cause cholestasis and subsequent pathological changes. FXR regulates the synthesis and uptake of bile acid via enzymes.
Zhi Qing, Yuan, Ke Wei, Li
openaire   +2 more sources

Nonacidic Farnesoid X Receptor Modulators

Journal of Medicinal Chemistry, 2017
As a cellular bile acid sensor, farnesoid X receptor (FXR) participates in regulation of bile acid, lipid and glucose homeostasis, and liver protection. Clinical results have validated FXR as therapeutic target in hepatic and metabolic diseases.
Daniel Flesch, Sun-Yee Cheung, Jurema Schmidt, Matthias Gabler, Pascal Heitel, Jan Kramer, Astrid Kaiser, Markus Hartmann, Mara Lindner, Kerstin Lüddens-Dämgen, Jan Heering, Christina Lamers, Hartmut Lüddens, Mario Wurglics, Ewgenij Proschak, Manfred Schubert-Zsilavecz, Daniel Merk   +16 more
openaire   +3 more sources

Antiatherosclerotic effect of farnesoid X receptor

American Journal of Physiology-Heart and Circulatory Physiology, 2009
The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily that functions as an endogenous sensor for bile acids and regulates cholesterol and fatty acid metabolism. The effect of FXR activation on aortic plaque formation was assessed by feeding apolipoprotein E-deficient (ApoE−/−) mice with the synthetic FXR ligand INT-747, a ...
MENCARELLI, Andrea, RENGA, Barbara, DISTRUTTI, ELEONORA, FIORUCCI, Stefano   +3 more
openaire   +3 more sources