Results 81 to 90 of about 16,980 (251)

Farnesol-derived Dicarboxylic Acids in the Urine of Animals Treated with Zaragozic Acid A or with Farnesol [PDF]

open access: yesJournal of Biological Chemistry, 1997
Farnesyl diphosphate, the substrate for squalene synthase, accumulates in the presence of zaragozic acid A, a squalene synthase inhibitor. A possible metabolic fate for farnesyl diphosphate is its conversion to farnesol, then to farnesoic acid, and finally to farnesol-derived dicarboxylic acids (FDDCAs) which would then be excreted in the urine.
R G, Bostedor   +7 more
openaire   +2 more sources

Phytochemical Composition and Potential Bioactivity With ADMET Analysis of Selected Species From Myrtaceae Family

open access: yesFlavour and Fragrance Journal, EarlyView.
Investigation of four medicinal plants of the family Myrtaceae. ABSTRACT Compounds derived from natural sources continue to serve as chemical scaffolds for designing prophylactic/therapeutic options for human healthcare. This study aimed to evaluate the phytochemical composition, antioxidant potential, in vitro anti‐inflammatory, antibacterial and ...
Archana Joshi   +8 more
wiley   +1 more source

Therapeutic Efficacy of Sesquiterpene Farnesol in Treatment of Cutibacterium acnes-Induced Dermal Disorders

open access: yesMolecules, 2021
Acne vulgaris is a highly prevalent skin disorder requiring treatment and management by dermatologists. Antibiotics such as clindamycin are commonly used to treat acne vulgaris.
Guan-Xuan Wu   +6 more
doaj   +1 more source

Elucidating Signal Transduction Modulatory Drug Target Network of Colon Cancer: A Network Biology Approach [PDF]

open access: yes, 2010
Latest evaluation and validation of cancer drugs and their targets has demonstrated the lack and inadequate development of new and better drugs, based on available protocols.
Biplab Bhattacharjee   +5 more
core   +1 more source

LsFAMeT and LsJHAMT coordinate JH biosynthesis to regulate fecundity in Laodelphax striatellus

open access: yesInsect Science, EarlyView.
The small brown planthopper (SBPH), Laodelphax striatellus, can trigger large‐scale outbreaks when encountering suitable habitats during migration due to their strong reproductive ability. This study investigated the role of juvenile hormone (JH) in regulating SBPH reproduction.
Yan Guo   +3 more
wiley   +1 more source

Transcriptional Profiling of the Candida auris Response to Exogenous Farnesol Exposure

open access: yesbioRxiv, 2021
Candida auris is a dangerous fungal pathogen that causes outbreaks in health care facilities, with infections associated with a high mortality rate. As conventional antifungal drugs have limited effects against the majority of clinical isolates, new and ...
Á. Jakab   +11 more
semanticscholar   +1 more source

Farnesol antimicrobial role as biofilm cell detachment inducer in S. epidermidis biofilms [PDF]

open access: yes, 2012
Objetives: Farnesol is a naturally-occurring sesquiterpene that was originally isolated from essential oils found in many plants has been described to have antimicrobial potential against several bacteria, including S. epidermidis.
Bento, Joana C.   +8 more
core  

Enterococcus faecalis and Endodontic Treatment Failure: A Qualitative Systematic Review of Its Role and Elimination Strategies

open access: yesAustralian Endodontic Journal, EarlyView.
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima   +1 more
wiley   +1 more source

Effects of Sucrose and Farnesol on Biofilm Formation by Streptococcus mutans and Candida albicans

open access: yesMicroorganisms
Candida albicans (C. albicans) and Streptococcus mutans (S. mutans) are frequently detected in the plaque biofilms of children with early childhood caries.
Wit Yee Wint   +5 more
semanticscholar   +1 more source

Trans,trans-farnesol, an antimicrobial natural compound, improves glass ionomer cement properties.

open access: yesPLoS ONE, 2019
A series of experiments were conducted to characterize a novel restorative material. We explored the effect on biological, physical and chemical properties of glass ionomer cement (GIC) adding-the naturally occurring tt-farnesol (900 mM). Two groups were
Aline Rogéria Freire de Castilho   +10 more
doaj   +1 more source

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