Results 61 to 70 of about 5,807 (179)

Farnesol-Detecting Olfactory Neurons inDrosophila [PDF]

The Journal of Neuroscience, 2014
We set out to deorphanize a subset of putativeDrosophilaodorant receptors expressed in trichoid sensilla using a transgenicin vivomisexpression approach. We identified farnesol as a potent and specific activator for the orphan odorant receptor Or83c. Farnesol is an intermediate in juvenile hormone biosynthesis, but is also produced by ripe citrus fruit
David S, Ronderos, Chun-Chieh, Lin, Christopher J, Potter, Dean P, Smith   +3 more
openaire   +2 more sources

Functional Stability and the Limits of 16S‐Based Inference in Serpentine Biocrusts

Ecological Research, Volume 41, Issue 4, July 2026.
Serpentine geochemistry and moisture regime shape bacterial biocrust communities in the Barberton Greenstone Belt, South Africa. While coarse taxonomic metrics (alpha and beta diversity) showed no significant differences, ASV‐level analyses revealed strong taxonomic shifts linked to soil chemistry and moisture, with numerous serpentine‐associated taxa ...
Danielle Botha, Sandra Barnard, Sarina Claassens, Stefan J. Siebert   +3 more
wiley   +1 more source

Candida albicans quorum-sensing molecule farnesol modulates staphyloxanthin production and activates the thiol-based oxidative-stress response in Staphylococcus aureus

Virulence, 2019
Microbial species utilize secreted-signaling molecules to coordinate their behavior. Our previous investigations demonstrated a key role for the Candida albicans-secreted quorum-sensing molecule farnesol in modulating Staphylococcus aureus response to ...
Taissa Vila, Eric F. Kong, Ahmed Ibrahim, Kurt Piepenbrink, Amol C. Shetty, Carrie McCracken, Vincent Bruno, Mary Ann Jabra-Rizk   +7 more
doaj   +1 more source

Ameliorative action of farnesol on cyclophosphamide induced toxicity in mice [PDF]

Journal of HerbMed Pharmacology, 2018
Introduction: Cyclophosphamide is an alkylating agent with antineoplastic and immunosuppressive effects. Acrolein, one of its metabolites, is responsible for different toxic side effects such as oxidative stress, and cell death.
Atefeh Araghi, Hannaneh Golshahi, Farshad Baghban, Mohaddeseh Abouhosseini Tabari   +3 more
doaj   +1 more source

Microbial Metabolite‐Stimulated Bitter Taste Receptor T2R14 Signaling Is Modulated by CFTR Interactions

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Bitter taste receptors (T2Rs) play an important role in physiological and cellular responses. Bitter tasting chemicals and microbial metabolites can bind to T2R14, which enables interactions between T2R14 and specific intracellular domains of the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel.
Tejas Gupte, Nisha Singh, Vikram Bhatia, Kavisha Arora, Shayan Amiri, Paul Fernyhough, Anjaparavanda P. Naren, Shyamala Dakshinamurti, Prashen Chelikani   +8 more
wiley   +1 more source

Antibiofilm and antifungal activities of medium‐chain fatty acids against Candida albicans via mimicking of the quorum‐sensing molecule farnesol

Microbial Biotechnology, 2021
Summary Candida biofilms are tolerant to conventional antifungal therapeutics and the host immune system. The transition of yeast cells to hyphae is considered a key step in C.
Jin‐Hyung Lee, Yong‐Guy Kim, Sagar Kiran Khadke, Jintae Lee   +3 more
doaj   +1 more source

Molecular mechanisms involved in farnesol-induced apoptosis [PDF]

Cancer Letters, 2010
The isoprenoid alcohol farnesol is an effective inducer of cell cycle arrest and apoptosis in a variety of carcinoma cell types. In addition, farnesol has been reported to inhibit tumorigenesis in several animal models suggesting that it functions as a chemopreventative and anti-tumor agent in vivo.
Joung Hyuck, Joo, Anton M, Jetten
openaire   +2 more sources

Traditional Respiratory Remedies From Anatolia: Ethnobotanical Insights and Bioactive Properties

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
ABSTRACT Respiratory disorders, ranging from acute viral infections such as influenza and bronchitis to chronic inflammatory conditions including chronic obstructive pulmonary disease, asthma, emphysema, and pneumonia, represent a major global health burden, affecting millions annually. Traditional Anatolian folk medicine has long relied on plant‐based
Golshan Zare, Yağmur Diker, Irem Tatlı Çankaya, Emran Habibi, Satyajit D. Sarker, Lutfun Nahar   +5 more
wiley   +1 more source

Farnesol stimulates laccase production in Trametes versicolor

Engineering in Life Sciences, 2016
Farnesol, a quorum‐sensing molecule, was used successfully to improve laccase production in submerged cultures of Trametes versicolor. At the optimal farnesol concentration of 60 μM added at the beginning of the culture, the extracellular laccase ...
Jianhua Hu, Feng Wang, Anzhou Ma, Guoqiang Zhuang, Ying Liu, Jingsong Lu, Chen Guo, Chunzhao Liu   +7 more
doaj   +1 more source

Repurposing Farnesol for Combating Drug-Resistant and Persistent Single and Polymicrobial Biofilms

Antibiotics
Biofilm-associated infections caused by drug-resistant and persistent bacteria remain a significant clinical challenge. Here we report that farnesol, commercially available as a cosmetic and flavoring agent, shows significant anti-biofilm properties when
Li Tan, Rong Ma, Tony Reeves, Adam J. Katz, Nicole Levi   +4 more
doaj   +1 more source