Results 41 to 50 of about 16,980 (251)

Farnesol Ameliorates Demyelinating Phenotype in a Cellular and Animal Model of Charcot-Marie-Tooth Disease Type 1A

open access: yesCurrent Issues in Molecular Biology, 2021
Charcot-Marie-Tooth disease (CMT) is a genetically heterogeneous disease affecting the peripheral nervous system that is caused by either the demyelination of Schwann cells or degeneration of the peripheral axon. Currently, there are no treatment options
Na-Young Park   +7 more
doaj   +1 more source

The Fungal Quorum-Sensing Molecule Farnesol Activates Innate Immune Cells but Suppresses Cellular Adaptive Immunity

open access: yesmBio, 2015
Farnesol, produced by the polymorphic fungus Candida albicans, is the first quorum-sensing molecule discovered in eukaryotes. Its main function is control of C. albicans filamentation, a process closely linked to pathogenesis.
Ines Leonhardt   +11 more
doaj   +1 more source

Antimicrobial effect of farnesol, a Candida albicans quorum sensing molecule, on Paracoccidioides brasiliensis growth and morphogenesis

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2009
Background Farnesol is a sesquiterpene alcohol produced by many organisms, and also found in several essential oils. Its role as a quorum sensing molecule and as a virulence factor of Candida albicans has been well described.
Silva-Pereira Ildinete   +6 more
doaj   +1 more source

Biofilm biomass disruption by natural substances with potential for endodontic use

open access: yesBrazilian Oral Research, 2013
This study evaluated the in vitro effects of four natural substances on the biomass of bacterial biofilms to assess their potential use as root canal irrigants.
Flávio Rodrigues Ferreira Alves   +3 more
doaj   +1 more source

The Biomedical Importance of the Missing Pathway for Farnesol and Geranylgeraniol Salvage

open access: yesMolecules, 2022
Isoprenoids are the output of the polymerization of five-carbon, branched isoprenic chains derived from isopentenyl pyrophosphate (IPP) and its isomer, dimethylallyl pyrophosphate (DMAPP).
I. Verdaguer   +3 more
semanticscholar   +1 more source

The fungal quorum-sensing molecule, farnesol, regulates the immune response of vaginal epithelial cells against Candida albicans

open access: yesBMC Microbiology, 2023
Background Farnesol is a Candida-secreted quorum-sensing molecule of great interest as a potential antifungal agent for serious and hardly curable infections—candidiasis, especially vulvovaginal candidiasis (VVC).
Ting Li   +8 more
doaj   +1 more source

Fungi at the scene of the crime: innocent bystanders or accomplices in oral infections? [PDF]

open access: yes, 2018
Purpose of Review: Over the last decade, microbiome studies have enhanced our knowledge and understanding of the polymicrobial nature of oral infections.
Delaney, Christopher   +6 more
core   +2 more sources

De novo formation of an aggregation pheromone precursor by an isoprenyl diphosphate synthase-related terpene synthase in the harlequin bug. [PDF]

open access: yes, 2018
Insects use a diverse array of specialized terpene metabolites as pheromones in intraspecific interactions. In contrast to plants and microbes, which employ enzymes called terpene synthases (TPSs) to synthesize terpene metabolites, limited information ...
Ghosh, Saikat Kumar B   +17 more
core   +3 more sources

Antibacterial, Antibiofilm, and Antiviral Farnesol-Containing Nanoparticles Prevent Staphylococcus aureus from Drug Resistance Development

open access: yesInternational Journal of Molecular Sciences, 2022
Multidrug antimicrobial resistance is a constantly growing health care issue associated with increased mortality and morbidity, and huge financial burden.
A. Ivanova   +8 more
semanticscholar   +1 more source

Farnesol and farnesal dehydrogenase(s) in corpora allata of the tobacco hornworm moth, Manduca sexta.

open access: yesJournal of Lipid Research, 1983
The metabolism of [3H]farnesol was studied in cell-free preparations of corpora allata from the tobacco hornworm, Manduca sexta, to assess the role of this presumed biosynthetic precursor of juvenile hormone (JH) III.
F C Baker   +3 more
doaj   +1 more source

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