Results 21 to 30 of about 16,980 (251)
PLoS ONE, 2023 Leishmaniasis is a zoonotic disease transmitted by an obligate intra-macrophage protozoan of the genus Leishmania through the infective bite of a vector sandfly.
Harshita Sharma +4 more
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Microbial Biotechnology, 2021 Summary Candida biofilms are tolerant to conventional antifungal therapeutics and the host immune system. The transition of yeast cells to hyphae is considered a key step in C.
Jin‐Hyung Lee +3 more
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Pharmaceutics, 2021 Most rotator cuff (RC) tears occur at the bone–tendon interface and cause disability and pain. Farnesol, a sesquiterpene compound, can exert antioxidative and anti-inflammatory effects and promote collagen synthesis.
Yen-Hung Lin +5 more
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Farnesol repurposing for prevention and treatment of Acinetobacter baumannii biofilms
BiofilmAcinetobacter baumannii has emerged as a multidrug-resistant (MDR) superbug by causing severe infections, with high mortality rates. The ability of A. baumannii to form biofilms significantly contributes to its persistence in diverse environmental and ...
Li Tan +3 more
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Restoration of the Phenotype of Dedifferentiated Rabbit Chondrocytes by Sesquiterpene Farnesol
Pharmaceutics, 2022 Osteoarthritis (OA) is a joint disorder characterized by the progressive degeneration of articular cartilage. The phenotype and metabolism behavior of chondrocytes plays crucial roles in maintaining articular cartilage function.
Guan-Xuan Wu +5 more
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Farnesol: An approach on biofilms and nanotechnology
Medical Mycology, 2021 Abstract Biofilms are important virulence factor in infections caused by microorganisms because of its complex structure, which provide resistance to conventional antimicrobials. Strategies involving the use of molecules capable of inhibiting their formation and also act synergistically with ...
Adelaide Fernandes Costa +2 more
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Frontiers in Physiology, 2023 Aims: Farnesol was identified 20 years ago in a search for Candida albicans quorum sensing molecules (QSM), but there is still uncertainty regarding many aspects of its mode of action including whether it employs farnesol transport mechanisms other than ...
Cory H. T. Boone +4 more
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Biologically Active Fluorescent Farnesol Analogs [PDF]
Chemistry & Biology, 2005 We describe ten polyene analogs of farnesol, typified by 3,7,11-trimethyl-2,4,6,8,10-dodecapentenaldehyde oxime, which preserve the length, cross-section, and approximate hydrophobicity of farnesol. Four of the ten display strong quorum-sensing activity in the human pathogen Candida albicans, with IC(50) values for inhibition of germ-tube formation as ...
Shchepin, Roman +4 more
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Molecules, 2023 The efflux systems are considered important mechanisms of bacterial resistance due to their ability to extrude various antibiotics. Several naturally occurring compounds, such as sesquiterpenes, have demonstrated antibacterial activity and the ability to
Jorge Ederson Gonçalves Santana +15 more
semanticscholar +1 more source
The effects of farnesol on cell death of C.albicans biofilms
International Dental Journal, 2023 Aim or Purpose: Farnesol inhibited C. albicans biofilm formation and decreased its drug resistance. The study investigated the effects and the possible mechanisms of farnesol on the cell death (necrosis or apoptosis) of C. albicans biofilms.
Prof Xin Wei
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