Results 11 to 20 of about 16,980 (251)
PLoS ONE, 2023 Leishmaniasis is a vector-borne parasitic infection caused by the infective bite of female Phlebotomine sandflies. Treatment of leishmaniasis by conventional synthetic compounds is met by challenges pertaining to adverse effects which call for the ...
Harshita Sharma +5 more
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Fermentation, 2023 The effect of farnesol, a sesquiterpene alcohol, on the production of laccases by Trametes versicolor and Pycnoporus sanguineus in pineapple waste solid-state fermentation was evaluated.
Emanueli Backes +7 more
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Farnesol brain transcriptomics in CNS inflammatory demyelination
Clinical Immunology, 2023 Farnesol (FOL) prevents the onset of experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis (MS).We examined the transcriptomic profile of the brains of EAE mice treated with daily oral FOL using next-generation sequencing (RNA-seq).Transcriptomics from whole brains of treated and untreated EAE mice at the peak of EAE was
Doyle, William J. +6 more
openaire +3 more sources
Enhancement of the antifungal activity of some antimycotics by farnesol and reduction of Candida albicans pathogenicity in a quail model experiment [PDF]
Veterinary World, 2022 Background and Aim: Clinical strains of microorganisms, including pathogenic yeast-like fungi (YLF), are resistant to currently used antifungal agents. Thus, it is relevant to study the combinations of existing antimicrobial drugs and a medicinal extract
Nadezhda Sachivkina +8 more
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Effect of Farnesol in Trichoderma Physiology and in Fungal–Plant Interaction
Journal of Fungi, 2022 Farnesol is an isoprenoid intermediate in the mevalonate (MVA) pathway and is produced by the dephosphorylation of farnesyl diphosphate. Farnesol plays a central role in cell growth and differentiation, controls production of ubiquinone and ergosterol ...
Rosa E. Cardoza +10 more
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Microbiology SpectrumCutaneous candidiasis, caused by Candida albicans, is a severe and frustrating condition, and finding effective treatments can be challenging. Therefore, the development of farnesol-loaded nanoparticles is an exciting breakthrough.
Ting Shen +11 more
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Reduction in Pathogenicity in Yeast-like Fungi by Farnesol in Quail Model
Animals, 2022 Candida albicans was the first eukaryotic microorganism to exhibit quorum-sensing through the secretion of the sesquiterpene E, farnesol. This molecule is generated by dephosphorylation of farnesyl pyrophosphate in the mevalonate biosynthetic pathway in ...
Nadezhda Sachivkina +7 more
doaj +2 more sources
Repurposing Farnesol for Combating Drug-Resistant and Persistent Single and Polymicrobial Biofilms
AntibioticsBiofilm-associated infections caused by drug-resistant and persistent bacteria remain a significant clinical challenge. Here we report that farnesol, commercially available as a cosmetic and flavoring agent, shows significant anti-biofilm properties when
Li Tan +4 more
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In vitro and in vivo Effect of Exogenous Farnesol Exposure Against Candida auris
Frontiers in Microbiology, 2020 The spreading of multidrug-resistant Candida auris is considered as an emerging global health threat. The number of effective therapeutic regimens is strongly limited; therefore, development of novel strategies is needed.
Fruzsina Nagy +12 more
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mBioCandida albicans, an opportunistic fungal pathogen, produces the quorum-sensing molecule farnesol, which we have shown alters the transcriptional response and phenotype of human monocyte-derived dendritic cells (DCs), including their cytokine secretion ...
Maria Batliner +13 more
doaj +2 more sources