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Cwh8 moonlights as a farnesyl pyrophosphate phosphatase and is essential for farnesol biosynthesis in Candida albicans [PDF]
mBioIn the opportunistic pathogen Candida albicans, hyphal growth and virulence factor expression are regulated by environmental and chemical cues. Farnesol is a secreted autoregulatory molecule that represses filamentation.
Daniel J. Gutzmann +7 more
doaj +2 more sources
Potential Anti-Inflammatory and Anti-Cancer Properties of Farnesol
Molecules, 2018 Farnesol, an acyclic sesquiterpene alcohol, is predominantly found in essential oils of various plants in nature. It has been reported to exhibit anti-cancer and anti-inflammatory effects, and also alleviate allergic asthma, gliosis, and edema.
Young Yun Jung +2 more
exaly +3 more sources
Purification and Characterization of a Novel NAD(P)+-Farnesol Dehydrogenase from Polygonum minus Leaves. [PDF]
PLoS ONE, 2015 Juvenile hormones have attracted attention as safe and selective targets for the design and development of environmentally friendly and biorational insecticides.
Nor-Ain-Shahajar Ahmad-Sohdi +3 more
doaj +1 more source
Frontiers in Physiology, 2023 Aims: Farnesol was identified 20 years ago in a search for Candida albicans quorum sensing molecules (QSM), but there is still uncertainty regarding many aspects of its mode of action including whether it employs farnesol transport mechanisms other than ...
Cory H. T. Boone +4 more
doaj +1 more source
PLoS ONE, 2023 Leishmaniasis is a vector-borne parasitic infection caused by the infective bite of female Phlebotomine sandflies. Treatment of leishmaniasis by conventional synthetic compounds is met by challenges pertaining to adverse effects which call for the ...
Harshita Sharma +5 more
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The effects of farnesol on cell death of C.albicans biofilms
International Dental Journal, 2023 Aim or Purpose: Farnesol inhibited C. albicans biofilm formation and decreased its drug resistance. The study investigated the effects and the possible mechanisms of farnesol on the cell death (necrosis or apoptosis) of C. albicans biofilms.
Prof Xin Wei
doaj +1 more source
Effect of Farnesol in Trichoderma Physiology and in Fungal–Plant Interaction
Journal of Fungi, 2022 Farnesol is an isoprenoid intermediate in the mevalonate (MVA) pathway and is produced by the dephosphorylation of farnesyl diphosphate. Farnesol plays a central role in cell growth and differentiation, controls production of ubiquinone and ergosterol ...
Rosa E. Cardoza +10 more
doaj +1 more source
Biomedicines, 2023 Chronic inflammation and elevated cytokine levels are closely associated with the progression of chronic kidney disease (CKD), which is responsible for the manifestation of numerous complications and mortality.
Aline Müller +4 more
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In vitro and in vivo Effect of Exogenous Farnesol Exposure Against Candida auris
Frontiers in Microbiology, 2020 The spreading of multidrug-resistant Candida auris is considered as an emerging global health threat. The number of effective therapeutic regimens is strongly limited; therefore, development of novel strategies is needed.
Fruzsina Nagy +12 more
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Biology, 2022 There is a substantial unmet need for the treatment of skeletal muscle mass loss that is associated with aging and obesity-related increases in FFA. Unsaturated FFAs stimulate the inflammatory gene expression in human skeletal myoblasts (SkMs).
Eva Mückter +4 more
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