Results 31 to 40 of about 16,980 (251)
Biomedicines, 2023 Chronic inflammation and elevated cytokine levels are closely associated with the progression of chronic kidney disease (CKD), which is responsible for the manifestation of numerous complications and mortality.
Aline Müller +4 more
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Medicina, 2023 Background and Objectives: Vulvovaginal candidiasis (VVC) is a mucous membrane infection, with an increased rate of antifungal resistance of Candida species.
Fatemeh Nikoomanesh +7 more
semanticscholar +1 more source
Biology, 2022 There is a substantial unmet need for the treatment of skeletal muscle mass loss that is associated with aging and obesity-related increases in FFA. Unsaturated FFAs stimulate the inflammatory gene expression in human skeletal myoblasts (SkMs).
Eva Mückter +4 more
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Deciphering fungal dimorphism: Farnesol's unanswered questions [PDF]
Molecular Microbiology, 2017 SummaryCandida albicans excretes E,E‐farnesol as a virulence factor and quorum sensing molecule that prevents the yeast to hyphal conversion. Polke et al. (2016) identified eed1Δ/Δ as the first farnesol hypersensitive mutant of C. albicans. eed1Δ/Δ also excretes 10X more farnesol and while able to form hyphae, it cannot maintain hyphae.
Nickerson, Kenneth, Atkin, Audrey L.
openaire +2 more sources
bioRxiv, 2023 Candida auris is frequently associated with biofilm-related invasive infections. The resistant profile of these biofilms necessitates innovative therapeutic options, where quorum sensing may be a potential target.
Á. Jakab +8 more
semanticscholar +1 more source
Farnesol-Induced Apoptosis in Candida albicans [PDF]
Antimicrobial Agents and Chemotherapy, 2009 ABSTRACT Farnesol, a precursor in the isoprenoid/sterol pathway, was recently identified as a quorum-sensing molecule produced by the fungal pathogen Candida albicans . Farnesol is involved in the inhibition of germination and biofilm formation by C. albicans and can be cytotoxic at
Shirtliff, Mark E. +7 more
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BMC Genomics, 2023 Background The quorum-sensing molecule farnesol, in opportunistic yeast Candida albicans, modulates its dimorphic switch between yeast and hyphal forms, and biofilm formation. Although there is an increasing interest in farnesol as a potential antifungal
Sima Mohammadi +4 more
doaj +1 more source
bioRxiv, 2023 Candida albicans is an efficient colonizer of human gastrointestinal tracts and skin and is an opportunistic pathogen. C. albicans exhibits morphological plasticity and the ability to switch between yeast and filamentous morphologies is associated with ...
Daniel Gutzmann +5 more
semanticscholar +1 more source
Cureus, 2023 Introduction: Increased colorectal carcinoma (CRC) and osteosarcoma prevalence, low survival rate, poor prognosis, and the limitations of existing anticancer therapies like side effects of drugs, non-specificity, short half-life, etc., pose a need for ...
Zakir Hussain Fathima Hinaz +3 more
semanticscholar +1 more source
Systematic analysis of protein expression in Candida albicans exposed to farnesol
Chinese Medical Journal, 2019 . Background:. The phenotypic switching of Candida spp. plays an important role in the development of vulvovaginal candidiasis (VVC). Farnesol, as a quorum-sensing molecule in Candida albicans, has the ability to prevent yeast-to-hyphal conversion in ...
Feng-Juan Wang, Zhao-Hui Liu, Peng Lyu
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