Journal of Applied Toxicology, EarlyView.ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro +5 more
wiley +1 more source
Association of combined folic acid and progesterone use with congenital malformations in women with vaginal bleeding during early pregnancy: a multicenter cohort study. [PDF]
Eur J Med ResWu JN +5 more
europepmc +1 more source
Retraction: Transforming growth factor-β1-regulated Fas/FasL pathway activation suppresses nucleus pulposus cell apoptosis in an inflammatory environment [PDF]
openalex +1 more source
The Immunoregulatory and Hematopoietic Effects of Momelotinib in a Murine Bone Marrow Failure Model
Journal of Clinical Laboratory Analysis, EarlyView.Momelotinib, a selective small‐molecule inhibitor of JAK1/2 and the bone morphogenic protein receptor kinase activin A receptor type I (ACVR1), exerts its effects by inhibiting the overactivation of the BMP/ACVR1/SMAD signaling pathway. This inhibition reduces hepcidin production in hepatocytes, and reduces inflammation, aberrant cytokine signaling ...
Yue Zhang +7 more
wiley +1 more source
Cytosolic Versus Lysosomal Lipolysis in Adipose Tissue: Opposing Roles in Cardiometabolic Disease. [PDF]
Arterioscler Thromb Vasc BiolYeh YS +5 more
europepmc +1 more source
Evaluation of Panoramic Acquisition Errors by Predoctoral Dental Students
Journal of Dental Education, EarlyView.Abstract Objectives Panoramic radiography is commonly used in the management of dental‐alveolar pathology. Novice clinicians are prone to technical errors that diminish the diagnostic quality of radiographs. The objective of this study was to analyze technical errors made during panoramic exposures by third‐year (D3) dental students in order to enhance
Zachary B. Featherstone +2 more
wiley +1 more source
Perceived Financial Strain and Adolescent Mental Health: Evidence from a Population-Based Study in South Tyrol, Italy. [PDF]
Children (Basel)Wiedermann CJ +5 more
europepmc +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Atopic dermatitis (AD) is a chronic, relapsing skin condition that significantly affects children and their families. Treatment ranges from topical to systemic therapies, but evidence on long‐term recurrence following different treatment strategies in paediatric AD remains limited.
Frederikke Seeberg +3 more
wiley +1 more source
Peripheral Levels of Selected Biomarkers in Patients with Post-Sarcoidosis Chronic Fatigue Syndrome. [PDF]
J Inflamm ResMałujło-Balcerska E +6 more
europepmc +1 more source
JEADV Clinical Practice, EarlyView.Rademikibart, a potent IL‐4Rα‐targeting antibody, achieved its primary endpoint as a treatment for adults with moderate‐to‐severe atopic dermatitis (AD) in the CBP‐201‐WW001 Phase 2 trial. There is a need for AD treatment options with convenient dosing intervals.
Jonathan I. Silverberg +2 more
wiley +1 more source