Fas-independent T-cell apoptosis by dendritic cells controls autoimmune arthritis in MRL/lpr mice.
PLoS ONE, 2012 BackgroundAlthough autoimmunity in MRL/lpr mice occurs due to a defect in Fas-mediated cell death of T cells, the role of Fas-independent apoptosis in pathogenesis has rarely been investigated. We have recently reported that receptor activator of nuclear
Takashi Izawa +10 more
doaj +1 more source
Signaling pathways for transduction of the initial message of the glycocode into cellular responses [PDF]
, 1998 The sugar units of glycan structures store information and establish an alphabet of life. The language of the oligosaccharide coding units is deciphered by receptors such as lectins and the decoded message can be transduced by multiple signaling pathways.
Gabius, Hans-Joachim, Villalobo, A.
core +2 more sources
Micro Pattern‐Based 3D Cell Culture Platform: An Overview of Technologies and Applications
Exploration, EarlyView.Micro patterns are characterized as a coating of specific adhesion matrices on substrates to support cell growth. An overview of micropattern technology to regulate single cell morphology and fates, further focusing on the micro pattern‐based 3D cell culture platform used in the non‐tumor and tumor researches.
Xinglong Zhu +8 more
wiley +1 more source
Hypothermia Inhibits Fas-Mediated Apoptosis of Primary Mouse Hepatocytes in Culture
Cell Transplantation, 2004 Apoptosis occurs during the isolation and even short-term storage and culture of hepatocytes, and in the pathogenesis of liver diseases, such as hepatic failure and hepatitis.
Tao Fu M.D., Ph.D. +7 more
doaj +1 more source
Journal of Neuroinflammation, 2019 Background Glaucoma is a complex, multifactorial disease where apoptosis, microglia activation, and inflammation have been linked to the death of retinal ganglion cells (RGCs) and axon degeneration.
Anitha Krishnan +4 more
doaj +1 more source
Pleural fluid soluble Fas ligand and tuberculous pleural effusion: a prospective diagnostic test accuracy study. [PDF]
J Thorac Dis, 2023 Wen XH +10 more
europepmc +1 more source
Advanced extracellular vesicle immunotherapy
FlexMat, EarlyView.A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang +6 more
wiley +1 more source
Interkingdom Interactions in the Gut: Ecological Mechanisms, Homeostasis, and Therapeutic Modulation
Gut Medicine, EarlyView.ABSTRACT The gut microbiota constitutes a highly complex and dynamic ecosystem that profoundly influences host physiology, metabolism, and immunity. This review provides an integrative overview of the mechanisms through which gut microorganisms—particularly bacteria and fungi—interact with host cells and with each other to maintain intestinal ...
Rui‐Qi Wei +5 more
wiley +1 more source
Blocking soluble Fas Ligand ameliorates pemphigus: PC111 efficacy in ex-vivo human pemphigus models. [PDF]
Front Immunol, 2023 Lotti R +8 more
europepmc +1 more source
Transient depletion of innate immunity in varicella infections in otherwise healthy children
Turkish Journal of Hematology, 2009 Objective: Varicella is a common childhood infection and has a number of complications in the unvaccinated population. Perforin, found in natural killer cells, is important for the killing of virally infected cells. For this reason, the aim of this study
Nursat Erdemli +5 more
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