Results 111 to 120 of about 59,326 (211)

Fas cell surface death receptor/Fas ligand genetic variants in gastric cancer patients: A case-control study. [PDF]

Indian J Med Res, 2022
Asgari R, Bidmeshkipour A, Mansouri K, Bakhtiari M, Mozafari H, Abdolmaleki A.   +5 more
europepmc   +1 more source

Deciphering the Functional Mechanisms of eIF3f in Tumors and Exploring Targeted Therapies

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Eukaryotic translation initiation factor 3 subunit F (eIF3f) is a critical component of the eIF3 complex and plays a pivotal role in diverse biological processes, including cell proliferation, apoptosis, adhesion, and transcriptional regulation.
Yujinpeng Hao, Jun Shao, Naqi Lian, Mianli Bian   +3 more
wiley   +1 more source

Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2. [PDF]

Elife, 2021
Jeong D, Kim HS, Kim HY, Kang MJ, Jung H, Oh Y, Kim D, Koh J, Cho SY, Jeon YK, Lee EB, Lee SH, Shin EC, Kim HM, Yi EC, Chung DH.   +15 more
europepmc   +1 more source

Eyes Toward the Clinic: Selective Inhibition and Degradation Approaches to Bromodomain‐Containing Proteins

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
The function of bromodomain‐containing proteins in regulating gene transcription is reviewed here, including the development of chemical probes and targeted protein degradation modalities (e.g., PROTACs). This extends to clinical efforts targeting the BET bromodomain‐containing proteins. Challenges of selectivity, future prospects, and the differential
Cole R. Scholtz, William C. K. Pomerantz
wiley   +1 more source

Super-Resolution Imaging of Fas/CD95 Reorganization Induced by Membrane-Bound Fas Ligand Reveals Nanoscale Clustering Upstream of FADD Recruitment. [PDF]

Cells, 2022
Frazzette N, Cruz AC, Wu X, Hammer JA, Lippincott-Schwartz J, Siegel RM, Sengupta P.   +6 more
europepmc   +1 more source

Advances in the Neurotoxic Mechanisms of Acrylamide and Multitarget Intervention Strategies of Natural Products

Food Frontiers, Volume 7, Issue 4, July 2026.
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du, Yifan Zhao, Li Dong, Chen Ma, Xiaosong Hu, Daotong Li, Fang Chen, Yinghua Luo   +7 more
wiley   +1 more source

The bioactivity of soluble Fas ligand is modulated by key amino acids of its stalk region. [PDF]

PLoS One, 2021
Kajikawa O, Herrero R, Chow YH, Hung CF, Matute-Bello G.   +4 more
europepmc   +1 more source

Dietary Polyphenols as Natural Modulators of NF‐κB Signaling in Inflammation‐Driven Non‐Communicable Diseases: Focus on Cancer

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam, Anas Shamsi, Syed Tasqeruddin, Moyad Shahwan   +3 more
wiley   +1 more source

Treatment with Mesenchymal Stromal Cells Overexpressing Fas-Ligand Ameliorates Acute Graft-versus-Host Disease in Mice. [PDF]

Int J Mol Sci, 2022
Vacaru AM, Mazilu AM, Dumitrescu M, Fenyo IM, Gafencu AV, Vacaru AM.   +5 more
europepmc   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source