Results 91 to 100 of about 59,326 (211)

Pleural fluid soluble Fas ligand and tuberculous pleural effusion: a prospective diagnostic test accuracy study. [PDF]

J Thorac Dis, 2023
Wen XH, Wen JX, Mu L, Cao XS, Yan L, Huang JH, Chen H, Jiang TW, Hu ZD, Niu Y, Zheng WQ.   +10 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Hypothermia Inhibits Fas-Mediated Apoptosis of Primary Mouse Hepatocytes in Culture

Cell Transplantation, 2004
Apoptosis occurs during the isolation and even short-term storage and culture of hepatocytes, and in the pathogenesis of liver diseases, such as hepatic failure and hepatitis.
Tao Fu M.D., Ph.D., Andres T. Blei, Noriaki Takamura, Tesu Lin, Danqing Guo, Honglin Li, Maurice R. O'gorman, Humberto E. Soriano   +7 more
doaj   +1 more source

A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma

Journal of Neuroinflammation, 2019
Background Glaucoma is a complex, multifactorial disease where apoptosis, microglia activation, and inflammation have been linked to the death of retinal ganglion cells (RGCs) and axon degeneration.
Anitha Krishnan, Andrew J. Kocab, David N. Zacks, Ann Marshak-Rothstein, Meredith Gregory-Ksander   +4 more
doaj   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Blocking soluble Fas Ligand ameliorates pemphigus: PC111 efficacy in ex-vivo human pemphigus models. [PDF]

Front Immunol, 2023
Lotti R, Hundt JE, Ludwig RJ, Hammers CM, Bennett B, Amato A, Amato A, Marconi A, Pincelli C.   +8 more
europepmc   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Transient depletion of innate immunity in varicella infections in otherwise healthy children

Turkish Journal of Hematology, 2009
Objective: Varicella is a common childhood infection and has a number of complications in the unvaccinated population. Perforin, found in natural killer cells, is important for the killing of virally infected cells. For this reason, the aim of this study
Nursat Erdemli, Şule Ünal, Hamza Okur, Gülten Seçmeer, Ateş Kara, Aytemiz Gürgey   +5 more
doaj  

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Engineering donor lymphocytes with Fas ligand protein effectively prevents acute graft-versus-host disease. [PDF]

Blood Adv, 2023
Shrestha P, Turan A, Batra L, Gulen AE, Sun Z, Tan H, Askenasy N, Shirwan H, Yolcu ES.   +8 more
europepmc   +1 more source