Blocking soluble Fas Ligand ameliorates pemphigus: PC111 efficacy in ex-vivo human pemphigus models. [PDF]
Lotti R +8 more
europepmc +1 more source
Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange +9 more
wiley +1 more source
A novel Fas ligand plays an important role in cell apoptosis of Crassostrea hongkongensis: molecular cloning, expression profiles and functional identification of ChFasL. [PDF]
Qin Y +9 more
europepmc +1 more source
Maximal Proliferation of Cytotoxic T Lymphocytes Requires Reverse Signaling through Fas Ligand [PDF]
Ivy Suzuki, Pamela J. Fink
openalex +1 more source
What's New? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma +11 more
wiley +1 more source
Mesenchymal stem cells (MSCs) have the potential to repair and regenerate ischemic heart tissue; however, the poor viability of transplanted MSCs in the ischemic region is a major obstacle to their therapeutic use.
Onju Ham +12 more
doaj +1 more source
Treatment of Mice with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Leads to Aryl Hydrocarbon Receptor-Dependent Nuclear Translocation of NF-κB and Expression of Fas Ligand in Thymic Stromal Cells and Consequent Apoptosis in T Cells [PDF]
Iris Camacho +4 more
openalex +1 more source
Cell death and life in cancer: mathematical modeling of cell fate decisions
Tumor development is characterized by a compromised balance between cell life and death decision mechanisms, which are tighly regulated in normal cells.
Barillot, Emmanuel +4 more
core +2 more sources

