Results 141 to 150 of about 123,724 (326)

Data from Fas Ligand Deficiency Impairs Tumor Immunity by Promoting an Accumulation of Monocytic Myeloid-Derived Suppressor Cells

open access: gold, 2023
Sanam Peyvandi   +10 more
openalex   +1 more source

Blocking soluble Fas Ligand ameliorates pemphigus: PC111 efficacy in ex-vivo human pemphigus models. [PDF]

open access: yesFront Immunol, 2023
Lotti R   +8 more
europepmc   +1 more source

Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange   +9 more
wiley   +1 more source

Efficacy and safety of fruquintinib combined with albumin‐bound paclitaxel as second‐line therapy for advanced gastric cancer following failure of PD‐1 inhibitor‐containing treatment (TACTIC GC‐01): A phase II single‐arm study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma   +11 more
wiley   +1 more source

Modulation of Fas–Fas Ligand Interaction Rehabilitates Hypoxia-Induced Apoptosis of Mesenchymal Stem Cells in Ischemic Myocardium Niche

open access: yesCell Transplantation, 2015
Mesenchymal stem cells (MSCs) have the potential to repair and regenerate ischemic heart tissue; however, the poor viability of transplanted MSCs in the ischemic region is a major obstacle to their therapeutic use.
Onju Ham   +12 more
doaj   +1 more source

Cell death and life in cancer: mathematical modeling of cell fate decisions

open access: yes, 2011
Tumor development is characterized by a compromised balance between cell life and death decision mechanisms, which are tighly regulated in normal cells.
Barillot, Emmanuel   +4 more
core   +2 more sources

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