Results 221 to 230 of about 97,027 (306)

Enhancing Lipidomics With High‐Resolution Ion Mobility‐Mass Spectrometry

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Lipids, indispensable yet structurally intricate biomolecules, serve as critical regulators of cellular function and disease progression. Conventional lipidomics, constrained by limited resolution for isomeric and low‐abundance species, has been transformed by ion mobility‐mass spectrometry (IM‐MS).
Gaoyuan Lu   +3 more
wiley   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

open access: yesPest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Lack of Fas/FasL Does Not Protect from Latent Herpes Simplex 1 Infection but Decreases Virus-Induced Neurodegeneration. [PDF]

open access: yesCells
Patrycy M   +9 more
europepmc   +1 more source

Evidence for Drop‐Like Nuclear Deformation in Sheared Endothelial Monolayers

open access: yesSmall, EarlyView.
Physiological shear stress smoothens endothelial monolayers by selectively eliminating less‐spread cells with tall, wrinkled nuclei. Nuclear volume and surface area remain constant, consistent with drop‐like deformation governed by geometric constraints.
Mohammad Mohajeri   +7 more
wiley   +1 more source

Leveraging Viscosity to Unlock the Osteogenic Potential of BMP‐2 Mimetic DWIVA

open access: yesSmall, EarlyView.
Dynamic interfaces based on supported lipid bilayers demonstrate that the osteogenic potential of the BMP‐2 mimetic DWIVA can be harnessed by modulating substrate viscosity. This work highlights that the viscous properties of the cellular microenvironment play a crucial role in the mechanosensitive regulation of growth factor activity.
Finlay Cunniffe   +5 more
wiley   +1 more source

Cytosolic Versus Lysosomal Lipolysis in Adipose Tissue: Opposing Roles in Cardiometabolic Disease. [PDF]

open access: yesArterioscler Thromb Vasc Biol
Yeh YS   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy