Results 191 to 200 of about 1,037,971 (316)

ACL Repair of a Tibial Spine Avulsion Fracture Using a Dual Suspensory All-Suture Construct With Additional Physeal Sparing Modified Lemaire LET. [PDF]

Video J Sports Med
Decilveo AP, Patel N, Hatch GFR.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Fashion in the Nineties Symposium: "1990s Fashion Ephemera: Trends, Desire, and Exclusivity"

Graphic designer Paul Boudens and assistant professor and director of the MA in Fashion Studies at The New School Parsons Paris Dr. Marco Pecorari discuss 90s Fashion Ephemera: Trends, Desire, and Exclusivity for The Museum at FIT's 26th academic ...

core  

MNISQ: A Large-Scale Quantum Circuit Dataset for Machine Learning in the NISQ Era. [PDF]

Sci Data
Placidi L, Hataya R, Mori T, Aoyama K, Morisaki H, Mitarai K, Fujii K.   +6 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Fashion in the Nineties Symposium: Patricia Mears, "Spectacle: Fashion on Parade"

MFIT Deputy Director Patricia Mears reviews the many groundbreaking runway shows from the 1990s for The Museum at FIT's 26th academic symposium “Reinvention and Restlessness: Fashion in the Nineties” on February 11, 2022.

core  

Tensile effects in peridynamic plates with circular holes. [PDF]

Meccanica
Damian S, Cavuoto R, Pugno NM, Fraldi M, Deseri L.   +4 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

100 Years of Fashion: Part One

The Museum at FIT is excited to present 100 Years of Fashion, a two-part introduction to the history of fashion from the late 19th century through the 1990s. These two videos were originally created for high school students enrolled in FIT's Summer Live,

core  

Rotational Stability in a Feline Sacroiliac Luxation Model: Biomechanical Comparison of Cannulated Compression Headless Screws and Cortical Screws Applied in Positional or Lag Fashion. [PDF]

Animals (Basel)
Klement J, Wieser J, Thorwächter C, Zablotski Y, Lorenz ND, Lauer S, Kornmayer M.   +6 more
europepmc   +1 more source