Results 121 to 130 of about 1,627,435 (306)

Comics, robots, fashion and programming: outlining the concept of actDresses [PDF]

open access: yes, 2009
This paper concerns the design of physical languages for controlling and programming robotic consumer products. For this purpose we explore basic theories of semiotics represented in the two separate fields of comics and fashion, and how these could be ...
Fernaeus, Ylva, Jacobsson, Mattias
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Interaction Design: Foundations, Experiments [PDF]

open access: yes, 2006
Interaction Design: Foundations, Experiments is the result of a series of projects, experiments and curricula aimed at investigating the foundations of interaction design in particular and design research in general.
Hallnäs, Lars, Redström, Johan
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Collaborative CoVE Projects for Digital Design in FE Teaching and Learning [PDF]

open access: yes
The Batley School of Art & Design CoVE in Digital Design is a catalyst for collaboration between local schools, colleges and the creative industries.
Lowe, Peter, Taylor, Andrew
core  

Perancangan Set Furnitur Dengan Pendekatan Fashion Brand Chanel [PDF]

open access: yes, 2017
At this time, a lot of socialite from the middle-upper class of society who can buying branded stuffs. Many fashion houses that release furniture collection with their well-known brand and otherwise a lot of furniture designer collaboration with fashion ...
Anlenxia, C. (Celvin)
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Pengembangan Kerajinan Tenun Lokal Gorontalo Menjadi Model-Model Rancangan Busana yang Khas dan Fashionable Guna Mendukung Industri Kreatif [PDF]

open access: yes, 2015
Penelitian ini bertujuan menemukan cara dalam pengembangan kerajinan tenun lokal Gorontalo dengan memanfaatkannya sebagai bahan rancangan busana dan pelengkap busana yang khas dan fashionable.
Hasmah, ., I Wayan, Sudana, Ulin, Naini
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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