Results 131 to 140 of about 1,619,545 (306)
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Thinking outside the blocks [PDF]
This paper outlines an ongoing PhD research with the aim to develop an alternative fashion design and garment construction process for the initial design stages, using a practice initiated in three dimensions. The paper was partly triggered by views that
Montgomery, Bruce, Wang, Mei-Wen
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
QR code design: From digital graphics to environmental, product and fashion design
Classification of design codes by the level of complexity of their design was cre-ated for the first time. The obtained results are key to understanding the role of the QR code as a full-fledged work of art in the context of modern design. In the future,
Mariia Vorobchuk +3 more
doaj +1 more source
Perancangan Set Furnitur Dengan Pendekatan Fashion Brand Chanel [PDF]
At this time, a lot of socialite from the middle-upper class of society who can buying branded stuffs. Many fashion houses that release furniture collection with their well-known brand and otherwise a lot of furniture designer collaboration with fashion ...
Anlenxia, C. (Celvin)
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
As an essential medium for the cultural narrative of architectural space, studying the cognitive transformation mechanisms of traditional ethnic decorative patterns is critical for their effective preservation and innovative application.
Peiyan Du +3 more
doaj +1 more source

