Results 191 to 200 of about 35,096 (229)
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FasL, leukocytes and vascular modeling
Nature Medicine, 2004The recent paper by Ishida et al.1 examines the role of leukocytes, specifically T lymphocytes, in vascular remodeling and vaso-obliteration in the rat eye. The authors conclude that T lymphocytes bind to the vasculature and model it by using Fas ligand (FasL) to prune the developing vessels.
Thomas A Ferguson, Patrick M Stuart
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Constitutive Expression of FasL in Thyrocytes
Science, 1998C. Giordano et al . ([1][1]) reported evidence that the ligand for Fas antigen (FasL) is constitutively expressed on thyroid follicular cells from both normal and Hashimoto's thyroiditis (HT) tissue, and that normal thyrocytes express Fas antigen only after induction with interleukin-1β (IL-1β).
Theophil A. Stokes +6 more
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FasL-Independent Activation of Fas
2007Fas death receptor (also named CD95 or APO-1) is physiologically activated through binding to its cognate ligand, FasL. Fas/FasL interaction induces oligomerization and aggregation of Fas receptor, leading eventually to apoptosis after protein-protein interac tions with adaptor and effector proteins.
Faustino Mollinedo, Consuelo Gajate
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The FasL-Fas Signaling Network
Science Signaling, 2003Fas ligand (FasL; also known as APO-1L or CD95L) belongs to the tumor necrosis factor (TNF) ligand family, and its corresponding receptor, Fas (also known as APO-1 or CD95), is a typical member of the death receptor subgroup of the TNF receptor superfamily. Both molecules were originally identified through their apoptosis-inducing capabilities.
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Science, 2000
The binding of a ligand to its receptor has always been viewed as the trigger for signal transduction to ensue. However, as [Golstein][1] explains in his Perspective, new findings ([ Chan et al .][2] and [ Siegel et al .][3]) suggest that the Fas receptor preassembles into trimers without the help of its ligand, and that this preassembly conditions ...
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The binding of a ligand to its receptor has always been viewed as the trigger for signal transduction to ensue. However, as [Golstein][1] explains in his Perspective, new findings ([ Chan et al .][2] and [ Siegel et al .][3]) suggest that the Fas receptor preassembles into trimers without the help of its ligand, and that this preassembly conditions ...
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[Expression of FasL in rat cryptorchidism].
Zhonghua nan ke xue = National journal of andrology, 2007To investigate the expression of FasL in rat cryptorchidism and its significance.Twenty-four male SD rats (22-day old) were randomly divided into two groups: unilateral cryptorchid group (n = 12) and pseudo-operation group (n = 12). When the rats were 110-day old, blood samples were taken and the rats were killed for analysis.
Dong, Cheng +4 more
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FasL associated factors and their potential role in the regulation of FasL expression
Signal Transduction, 2005Jing Qian +3 more
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Nanoscale FasL Organization on DNA Origami to Decipher Apoptosis Signal Activation in Cells
Small, 2021Tim Liedl +2 more
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