Results 131 to 140 of about 19,974 (255)

Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero   +5 more
wiley   +1 more source

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

Insulin preserves fast-twitch muscle mass during early STZ-induced diabetes in rats. [PDF]

open access: yesBiochem Biophys Rep
Yamasaki Y   +14 more
europepmc   +1 more source

Physiological mechanisms underlying enhanced performance with blood flow restriction training: neuromuscular, vascular and metabolic adaptations

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We investigated how 6 weeks of dynamic knee‐extensor interval training with blood flow restriction (BFR‐leg) and without (CTRL‐leg) impacts performance and its mechanisms using non‐invasive methods. Specifically, we used gold‐standard methods to assess neuromuscular function, vascular function using Doppler ultrasound, and near ...
Colin Lavigne   +5 more
wiley   +1 more source

Skeletal muscle adaptation to muscle activity and hypoxia: Differential structural and metabolic remodelling

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend There has been controversy about the structural (capillary) response of skeletal muscle to altered O2 status, involving decreased supply (hypoxia) or increased demand (activity). Here we demonstrate that seven days of activation of skeletal muscle by indirect electrical stimulation led to significant expansion of the capillary ...
David Hauton   +3 more
wiley   +1 more source

Low‐threshold cutaneous mechanoreceptors on the foot sole have enhanced sensitivity when skin temperature is elevated

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of microneurography recordings used to examine the effects of local skin heating on cutaneous mechanoreceptor responses in the human foot (left panel). A microelectrode inserted into a peripheral nerve records single‐unit activity from tactile afferent fibres while controlled mechanical stimuli are applied ...
Erika E. Howe   +4 more
wiley   +1 more source

Piperine disrupts the OFF state of the resting thick filament of rat skeletal muscle, enhancing dynamic contractility in a fibre-type-dependent manner. [PDF]

open access: yesJ Physiol
Abstract figure legend We investigated the effects of piperine on (1) the structure of the resting thick filament and (2) dynamic contractility in fibres and intact slow (soleus) and fast (extensor digitorum longus, EDL) rat muscles, respectively. The structure of the resting thick filament was assessed pre‐ and post‐piperine incubation using small ...
Kruse DZ   +5 more
europepmc   +2 more sources

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