Results 171 to 180 of about 19,974 (255)

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou   +12 more
wiley   +1 more source

Livestock Multi‐Omics Integration: A Systematic Framework From Statistical Association to Causal Interpretation

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen   +5 more
wiley   +1 more source

Designing Tissue Function Through Embedded Bioprinting Architectures

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
Embedded bioprinting enables soft, cell‐dense constructs to be fabricated within supporting bath environments. This review introduces a function‐guided framework linking target tissue functions to architectural requirements, supporting bath selection, bioink design, printing dynamics, and validation assays.
Qi Li   +4 more
wiley   +1 more source

Interactions Between E3 Ubiquitin Ligases and Deubiquitinases in AKT Regulation: Implications in Skeletal Muscle Homeostasis

open access: yesCell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT AKT (protein kinase B, PKB) coordinates the balance between anabolic and catabolic signaling in skeletal muscle through distinct ubiquitin chain types. Some E3 ubiquitin ligases (E3s) and deubiquitinases (DUBs) form stable binary complexes via non‐catalytic interfaces, adding a regulatory layer unavailable to either enzyme alone.
Rajesh Dabur
wiley   +1 more source

Paroxysmal slow waves mark ictal networks

open access: yesEpilepsia, Volume 67, Issue 9, Page 4787-4802, September 2026.
Abstract Objective Epilepsy diagnosis and treatment monitoring are hindered by the episodic, heterogeneous expression of seizures and by normal‐appearing scalp electroencephalography (EEG) in many patients. We previously described paroxysmal slow‐wave events (PSWEs), brief epochs of broadband slowing detectable on EEG in people with epilepsy.
Florent J. M. Boyer‐Aymé   +13 more
wiley   +1 more source

Repetitive Transcranial Magnetic Stimulation in Alzheimer's Disease Cognitive Impairment: A Narrative Review of Clinical Trials

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Alzheimer's disease (AD), primarily characterized by cognitive impairment, places an immense burden on patients and caregivers. Non‐invasive neuromodulation with repetitive transcranial magnetic stimulation has been proposed to improve cognition in mild to moderate AD. This narrative review aimed to summarize clinical trial
Tejiri Napoleon   +17 more
wiley   +1 more source

Imeglimin Attenuates Skeletal Muscle Atrophy in Mouse Models of Obesity and Ageing. [PDF]

open access: yesJ Cachexia Sarcopenia Muscle
Ye Y   +7 more
europepmc   +1 more source

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