Results 161 to 170 of about 19,974 (255)

Experimental studies on mouse slow and fast twitch muscles

open access: yes, 2006
This thesis deals with physiological and mechanical properties of fast and slow twitch mouse muscles. It discusses isometric, concentric and eccentric contractions of mouse extensor digitorum longus ('EDL') and soleus ('SOL') muscles. This project primarily investigated the behaviors of muscles, to give better understanding and improved descriptions ...
openaire   +1 more source

Repeated Moderate and Severe Heat Exposure Has Divergent Effects on Skeletal Muscle Mitochondrial, Proteostatic and Neuromuscular Outcomes in Mice

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim Repeated heat exposure may promote adaptive remodeling or cumulative tissue burden depending on thermal dose, but its graded molecular and functional consequences during recovery remain unclear. We examined whether repeated moderate (39°C) and severe (41°C) whole‐body hyperthermia produce distinct skeletal muscle trajectories involving ...
Cansu Yakin   +4 more
wiley   +1 more source

A Biomimetic 3D Human Skeletal Muscle Microtissue for Modeling Biological and Functional Hallmarks of Aging. [PDF]

open access: yesSmall Sci
A biomimetic 3D human skeletal muscle microtissue platform is developed by integrating primary young and aged SkMCs with muscle‐derived dECM and 3D‐printed PCL anchors. Aged constructs recapitulate selected biological and functional hallmarks of skeletal muscle aging, including impaired myotube formation, mitochondrial alterations, calcium handling ...
Yang S   +9 more
europepmc   +2 more sources

Innovative Dose–Response Assessment of the Metaboreflex With Indirect Control of Intramuscular Metabolic Perturbation in Humans

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim We aimed to evaluate an innovative dose–response approach to assess the metaboreflex with control of intramuscular metabolic perturbation (concept of metaboreflex gain). We also investigated potential sex differences in the metaboreflex using this new approach.
Nabil Kouzkouz   +6 more
wiley   +1 more source

Exercise and Autonomic Cardiovascular Function—Insights From Spinal Cord‐Injured Humans: A Narrative Review

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT The cardiovascular response to acute exercise is mediated by the autonomic nervous system (ANS) control mechanisms that modulate vascular resistance to support blood pressure and ensure adequate blood flow to active muscles. These autonomic neurocirculatory control mechanisms include a feedforward mechanism, known as central command, and three
Rasmus Kopp Hansen   +5 more
wiley   +1 more source

Relaxin‐2: Shaping the Proteomic Landscape of Skeletal Muscle Physiology, Glucose Trafficking, and Mitochondrial Function in Rat

open access: yesThe FASEB Journal, Volume 40, Issue 18, 30 September 2026.
Cardioprotective hormone relaxin‐2 showed relevant effects on rat skeletal muscle by altering proteins linked to muscle function, regeneration, differentiation, mitochondrial function, glucose metabolism, and structural integrity and organization. Specifically, relaxin‐2 reduced the expression of 95 proteins, increased 32, and elicited unique proteins ...
Xocas Vázquez‐Abuín   +11 more
wiley   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

open access: yesAdvanced Materials Technologies, Volume 11, Issue 17, 3 September 2026.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger   +9 more
wiley   +1 more source

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