Results 81 to 90 of about 19,057 (240)

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

Quantitative Spatiotemporal Analysis of Ultrasound Images of Fasciculations in ALS

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Fasciculations are a hallmark of amyotrophic lateral sclerosis (ALS), yet quantitative description of individual events on muscle ultrasound (MUS) is limited. We characterized the spatiotemporal kinematics of individual fasciculations to determine whether they differ between ALS and other neurogenic conditions.
Ryosuke Sugisawa, Kenji Sekiguchi, Yoshikatsu Noda, Shun Matoba, Hirotomo Suehiro, Jun Kozuki, Tomoko Tanaka, Norio Chihara   +7 more
wiley   +1 more source

Comparison of the Effects of Retraining After Lower Limb Suspension on the Expression of MURF1 and TRAF6 Genes in Slow- and Fast-Twitch Muscles of Male Rats [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Exercise interventions are recognized as effective strategies for mitigating muscle atrophy. The present study aimed to investigate the effects of retraining, administered both before and after a period of lower limb suspension ...
Sudabeh Hassanshahi, Abdolreza Kazemi, Ayat Kaeidi   +2 more
doaj  

Differential regulation of MMP activity by TGFβ1 in fast- and slow- twitch muscle repair: insights from EDL and soleus muscle-derived myoblasts

Frontiers in Cell and Developmental Biology
IntroductionSkeletal muscles are characterized by a significant ability to regenerate in response to injury. However, muscle repair is often inefficient and hindered by the development of fibrosis.
Paulina Kasprzycka, Maria Anna Ciemerych, Malgorzata Zimowska   +2 more
doaj   +1 more source

Effects of eccentric contraction on force enhancement in rat fast-twitch muscle. [PDF]

Physiol Rep, 2023
Shi J, Wada M.
europepmc   +1 more source

With Regard to the Expression Status of Sarcolemmal Aquaporin 4 in Human Muscular Dystrophies

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Human muscular dystrophies are inherited muscle‐wasting diseases caused by the various kinds of gene mutations. Among them, Duchenne muscular dystrophy (DMD) is a representative type. Before the discovery of the causative dystrophin gene of DMD, the fragile myofiber plasma membrane was thought to be the trigger of myofiber necrosis in DMD ...
Yoshihiro Wakayama, Takahiro Jimi
wiley   +1 more source

Neuromuscular Monitoring of Rocuronium 0.6 mg/kg in Children Aged 3–24 Months With Electromyography and Acceleromyography: An Observational Study

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Objective neuromuscular monitoring is essential to prevent residual neuromuscular block in patients receiving neuromuscular blocking agents. However, the small size of pediatric hands and the lack of appropriately sized neuromuscular equipment have made quantitative neuromuscular monitoring at the ulnar nerve (UN) difficult. In such
Sarah Sofie Wadland, Karl Peter Damgård Madsen, Mikkel Helmuth Jensen, Magnus Fuhr Hovind, Morten Sonne, Morten Bøttger, Arash Afshari, Frederik Mondrup, Matias Vested   +8 more
wiley   +1 more source

Isolation of the Sarcoplasmic Reticulum Ca²⁺-ATPase from Rabbit Fast-Twitch Muscle. [PDF]

Methods Protoc, 2023
Rivera-Morán MA, Sampedro JG.
europepmc   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

PROTEOMICS, EarlyView.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling, Dounia Bouragba, Elisa Negroni, Capucine Trollet, Margit Zweyer, Dieter Swandulla, Kay Ohlendieck   +6 more
wiley   +1 more source

Effect of a virtual walking and therapeutic exercise‐based intervention on gait and balance in people with incomplete spinal cord injury

PM&R, EarlyView.
Abstract Background People with spinal cord injury (SCI) experience sensory and motor impairments that often require exercise‐based treatments. However, these interventions are challenging due to limited active mobility. Novel rehabilitation approaches, such as those targeting the mirror neuron system, could offer additional benefits.
Sara Mollà‐Casanova, Elena Muñoz‐Gómez, Núria Sempere‐Rubio, Noemí Moreno‐Segura, Marta Inglés, Luis‐Millán González, Pilar Serra‐Añó   +6 more
wiley   +1 more source