Results 271 to 280 of about 10,265,437 (389)

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

FAST NEUTRON SPECTRA FROM THE WATER BOILER

, 1951
Jeffrey F. Evans
openalex   +2 more sources

Bayesian meta-analysis reveals the mechanistic role of slow oscillation-spindle coupling in sleep-dependent memory consolidation. [PDF]

Elife
Ng T, Noh E, Spencer RMC.
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

REPROCESSING OF POWER REACTOR FUELS. The Enrico Fermi Fast Breeder Reactor Fuel Progress Report No. 2

, 1959
C.W. Pierce
openalex   +2 more sources

Clinical Significance of a Multicancer Screening Trial With Stage-Based End Points.

JAMA Netw Open
Gogebakan KC, Lange J, Owens L, Pinderup A, Gulati R, Kessler LG, Lyratzopoulos G, Etzioni R.   +7 more
europepmc   +1 more source

Monitoring intracellular replication dynamics unveils high proportion of non-replicating antibiotic-tolerant Staphylococcus aureus inside osteoblasts. [PDF]

PLoS Pathog
Marro FC, Brocard J, Faure A, Sion A, Verhoeven PO, Canonne-Desbiolles L, Conraux L, Jaffrelot L, Monlong C, Blocker AJ, Dubarry N, Laurent F, Josse J.   +12 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Evaluating Glasgow-Blatchford score for fast-track emergency management of patients with acute upper gastrointestinal bleeding. [PDF]

World J Gastrointest Surg
Zhang DQ, Zhou Q, Li YF, Jia XY, Li X, Chen S, Lin K.   +6 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source