Results 61 to 70 of about 179,951 (271)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

A quasi-analytical model for energy-delay-reliability tradeoff studies during write operations in perpendicular STT-RAM cell

, 2012
One of the biggest challenges the current STT-RAM industry faces is maintaining a high thermal stability while trying to switch within a given voltage pulse and energy cost.
Butler, William H., Ghosh, Avik W., Munira, Kamaram   +2 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Studi Efektifitas Indikator Kestabilan Tegangan Pada Model Dinamis Sistem Tenaga Listrik

Semesta Teknika, 2016
The paper presents the effectiveness of voltage stability indices for dynamic power system modelling study in providing information about the proximity of voltage collapse in power system.
Muhammad Nizam
doaj  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Optimal Allocation of Generalized Power Sources in Distribution Network Based on Multi-Objective Particle Swarm Optimization Algorithm

MATEC Web of Conferences, 2017
Optimal allocation of generalized power sources in distribution network is researched. A simple index of voltage stability is put forward. Considering the investment and operation benefit, the stability of voltage and the pollution emissions of ...
Li Ran, Yuan Jingwei, Song Yundong, Yang Yingxuan, Meng Tao   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Overview of increasing the penetration of renewable energy sources in the distribution grid by developing control strategies and using ancillary services [PDF]

, 2014
Increasing the renewables energy resources in the distribution network is one of the main challenges of the distributed system operator due to instability, power quality and feeder capacity problems. This paper proposes a solution for further penetration
Bozalakov, Dimitar, Meersman, Bart, Vandevelde, Lieven, Vandoorn, Tine   +3 more
core  

Fixed field alternating gradient

, 2013
The concept of a fixed field alternating gradient (FFAG) accelerator was invented in the 1950s. Although many studies were carried out up to the late 1960s, there has been relatively little progress until recently, when it received widespread attention ...
Machida, Shinji
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source