Results 81 to 90 of about 21,407 (261)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Voltage collapse prediction and control of a power system using hybridized classical probability theory and voltage stability indices

Discover Electronics
The incessant voltage collapse incidences on the Nigeria National grid is a serious concern. The primary dependability issue of voltage collapse makes it difficult to operate a reliable and secure power system network.
O. F. Amakiri, G. Ofualagba, J. N. Onah
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Voltage stability index for under voltage load sheeding scheme

, 2010
Power system is a nonlinear system that operates in a constantly changing environment. When subjected to a disturbance, the stability of the system depends on the initial operating condition as well as the nature of the disturbance.
Zahidi, Rubiatul Adawiyah
core  

Voltage stability assessment of power systems using voltage stability indices and artificial intelligence techniques [PDF]

, 2012
The research presented in this thesis uses the Artificial Intelligence (AI) techniques to assess the voltage stability condition in power systems. Voltage stability index is a feature for evaluating the voltage stability condition.
Mehdi, Omer Hikmat
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A new weak area identification method in power system based on voltage stability. [PDF]

, 2017
Identification of voltage stability weak area in power system plays an important role in preventing the occurrence of voltage collapse. A fast and accurate identification method helps power system operators to apply voltage stability control action on ...
Yasin, Zuhaila Mat, Aziz, Nur Fadilah Ab, Rahman, Titik Khawa Abdul, Salim, Nur Ashida, Muhammad-Sukki, Firdaus, Rahmat, Nur Azammudin, Wahab, Norfishah A., Yassin, Zuhaila Mat   +7 more
core   +3 more sources

Voltage Stability Prediction on Power Networks using Artificial Neural Networks

, 2018
 The objective of this paper is to predict the secure or the insecure state of the power system network using a hybrid technique which is a combination of Artificial Neural Network (ANN) and voltage stability indexes.
Das, Priyanath, Saha, Gitanjali, Chakraborty, Kabir   +2 more
core   +2 more sources

Voltage Stability Enhancement in Power Distribution Systems using an Improved Blue Monkey Optimization-Based D-SVCs Integration Approach

Journal of Electrical Engineering and Computer
This paper presents an Improved Blue Monkey (IBM) optimization algorithm for enhancing voltage stability and reducing power losses in distribution networks through optimal placement and sizing of Distribution Static Var Compensators (D-SVCs).
Abigail Obeng
doaj   +1 more source