Results 71 to 80 of about 21,407 (261)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Voltage Stability Assessment and Enhancement in Power Systems [PDF]

open access: yes, 2019
Voltage stability is a long standing issue in power systems and also is critical in the power system. This thesis aims to address the voltage stability problems.
LIU, QITAO
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

ANALISIS STABILITAS TEGANGAN SISTEM TENAGA LISTRIK 500 kV JAWA BALI DENGAN FAST VOLTAGE STABILITY INDEX (FVSI

open access: yes, 2013
500 kV Java Bali electric power system is vital and Voltage stability is one factor to be considered in planning and operation of electrical power systems.
, HARYO PRATIKTO   +1 more
core  

Evaluation of Some Indices for Voltage Stability Assessment

open access: yes, 2009
The liberalization of the electricity markets causes power systems to work closer and closer to their limits. The online assessment of system security becomes a topic of paramount importance in control centers.
S. Massucco   +4 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Determination of Fast Voltage Stability Index (FVSI) using Evolutionary Programming (EP) technique to maintain system stability / Norhafizah Zulkipli [PDF]

open access: yes, 2014
Nowadays, electrical energy used is increasing from day onwards, so in order to meet the demand, power systems are operating closer to their maximum capacity which will cause higher risk to the power system instability. It also will cause the shutdown of
Zulkipli, Norhafizah
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Multi-objective simultaneous DG and DSTATCOM allocation in radial distribution networks using cuckoo searching algorithm

open access: yesAlexandria Engineering Journal, 2018
In this paper, authors proposed a new methodology based on bio-inspired Cuckoo Search Algorithm (CSA), which can significantly be envisaged with simultaneous allocation of Distributed Generation (DG) and Distribution STATic COMpensator (DSTATCOM) in the ...
T. Yuvaraj, K. Ravi
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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