Results 81 to 90 of about 179,951 (271)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Fast Assessment Method for Transient Voltage Stability of Photovoltaic Receiving‐End Grid
The incorporation of renewable energy on a broad scale into power grids increases the complexity to the issue of transient voltage stability in power systems.
Ying Qu +5 more
semanticscholar +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Smart grids for rural conditions and e-mobility - Applying power routers, batteries and virtual power plants [PDF]
Significant reductions of greenhouse gas emission by use of renewable energy sources belong to the common targets of the European Union. Smart grids address intelligent use and integration of conventional and renewable generation in combination with ...
Boehner, Volker +6 more
core
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Single-Frequency, Thin-Film-Tuned, 0.6W, Diode-Pumped Nd:YVO\u3csub\u3e4\u3c/sub\u3e Laser [PDF]
Application of a metallic thin-film selector to the single-frequency oscillation of a diode-pumped Nd:YVO4 laser has been investigated theoretically and experimentally.
Firak, Józef +2 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Impact of the UPFC on the optimal transmission switching for cutting down market power cost [PDF]
The exercise of market power by the strategic generating companies (gencos) in the deregulated wholesale electricity market (WEM) should be mitigated, as it results in higher wholesale prices of electricity and a drop in competition in the WEM ...
Sunday Adetona +3 more
doaj +1 more source

