Results 81 to 90 of about 8,890 (312)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 1915 Patent for a fastener to be used in the connection of doors to ensure they are locked into ...
Wilson, William W.
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Engineering Verification of Key Technologies for Rail Transit Stray Current Protection
Chengshi guidao jiaotong yanjiu[Objective] In order to solve the problem of stray current corrosion on metro lines, it is necessary to conduct engineering verification of the key technologies for stray current protection in urban rail transit.
JIN Shoujie +5 more
doaj +1 more source
, 1903 Patent for a fastener. This invention is an improved design for "securing the eyes to traces or tugs or fastening stirrup-leathers together" (line 9-11).
Gardner, Eugene Silas
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
, 1915 Patent for a new End-Gate Fastener, accompanied by several illustrations of form and function. Specific claims to the End-Gate Fastener include: transverse rods designed to mount device for easy removable and replacement of device on wagons, transverse ...
Nichols, George Thomas
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source