Results 91 to 100 of about 10,086,978 (282)

Nutritional status and structural brain changes in Alzheimer's disease: The NUDAD project

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020
Introduction Weight loss is associated with higher mortality and progression of cognitive decline, but its associations with magnetic resonance imaging (MRI) changes related to Alzheimer's disease (AD) are unknown.
Barbara J.H. Verhaar, Francisca A. deLeeuw, Astrid S. Doorduijn, Jay L.P. Fieldhouse, Ondine van deRest, Charlotte E. Teunissen, Bart N.M. vanBerckel, Frederik Barkhof, Marjolein Visser, Marian A.E. de van derSchueren, Philip Scheltens, Maartje I. Kester, Majon Muller, Wiesje M. van derFlier   +13 more
doaj   +1 more source

Reference Data for Fat Mass and Fat-Free Mass Measured by Bioelectrical Impedance in Croatian Youth

, 2021
Fat mass and fat-free mass have become useful clinical indices in determining healthy growth and physical development during critical periods of childhood and adolescence; however, despite a wide range of nutritional surveillance its study is limited by ...
Vilko Petrić, Mario Kasović, Boris Neljak, Lovro Štefan, Damir Knjaz   +4 more
core   +1 more source

Body composition, physical fitness and cardiovascular risk factors in 9-year-old children

Scientific Reports, 2022
The independent associations of body composition and physical fitness components with cardiovascular disease (CVD) risk factors in childhood are not fully understood.
Pontus Henriksson, Johanna Sandborg, Maria Henström, Christine Delisle Nyström, Evelina Ek, Francisco B. Ortega, Marie Löf   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Relation of body fat mass and fat-free mass to total mortality: results from 7 prospective cohort studies

, 2021
Background: Fat mass and fat-free mass may play independent roles in mortality risk but available studies on body composition have yielded inconsistent results.
Fischer, Beate, Völzke, Henry, Baumeister, Sebastian Edgar, Felix, Stephan B., Dörr, Marcus, Sedlmeier, Anja M., Peters, Annette, Leitzmann, Michael F., Thorand, Barbara, Weber, Andrea, Ittermann, Till, Baumeister, Sebastian E.   +11 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Improved recovery from prolonged exercise following the consumption of low glycemic index carbohydrate meals [PDF]

, 2005
The present study examined the effects of the glycemic index (GI) of post-exercise carbohydrate (CHO) intake on endurance capacity and the metabolic responses during exercise the following day. Nine active males participated in two trials in a randomised
Oram, Chris, Williams, Clyde, Stevenson, Emma, McComb, Gareth   +3 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Quantifying Obesity in Economic Research: How Misleading is the Body Mass Index? [PDF]

Replaced with revised version of paper 07/19/10.Obesity, percent body fat (PBF), body mass index (BMI), economic costs, measurement error, Health Economics and Policy, Research and Development/Tech Change/Emerging Technologies, C52, I10,
Smith, Aaron D., Parks, Joanna C., Alston, Julian M.   +2 more
core