Results 81 to 90 of about 323,149 (300)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Body composition in patients with schizophrenia: Comparison with healthy controls

Annals of General Psychiatry, 2012
Background Recently, a relationship between obesity and schizophrenia has been reported. Although fat- mass and fat free mass have been shown to be more predictive of health risk than body mass index, there are limited findings about body composition ...
Sugawara Norio, Yasui-Furukori Norio, Tsuchimine Shoko, Fujii Akira, Sato Yasushi, Saito Manabu, Matsuzaka Masashi, Takahashi Ippei, Kaneko Sunao   +8 more
doaj   +1 more source

Age and gender-related fat mass index and fat- free mass index patterns among adolescents in Surulere LGA, Lagos

, 2014
Background: Percent body fat, fat mass and fat mass index are measures of body fat while fat free mass and fat free mass index measure lean mass. These measures of body composition vary with age and sex.Aim: To show the age-related patterns of measures ...
Okoromah, CAN, David, AN, Nwizu, SE, Njokanma, OF   +3 more
core   +1 more source

Body fat distribution, fat-free mass and cardiovascular function in the UK Biobank

, 2023
Background: Excess adiposity and high body mass index have been associated with cardiac dysfunction and heart failure. However, the role of whole body imaging and independent associations of regional fat and fat-free mass on left ventricular and vascular
Taylor, Hannah, Lewington, Sarah, Oguntade, Ayodipupo, Lacey, Ben   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Analyses of body composition charts among younger and older Chinese children and adolescents aged 5 to 18 years

BMC Public Health, 2012
Background Childhood obesity has become a major public health problem in China. The objective of this study was to examine the effect of age and sex on the relationship between fat-free mass (FFM) and fat mass (FM), fat-free mass index (FFMI) and fat ...
Xiong Kai-Yu, He Hui, Zhang Yi-Ming, Ni Guo-Xin   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Assessing body composition by bioelectric impedance analysis and dual-energy X-ray absorptiometry in physically active normal and overweight Indian males

National Journal of Physiology, Pharmacy and Pharmacology, 2018
Background: To improve body composition measurement methods for physically active healthy individuals, validation with of bioelectric impedance analysis (BIA) with using dual-energy X-ray absorptiometry (DXA) on basis of variation in body mass index (BMI)
Daisy Masih, Gurseen Rakhra, Annu Vats, Saroj Kumar Verma, Yogendra Kumar Sharma, Som Nath Singh   +5 more
doaj   +1 more source

Improved recovery from prolonged exercise following the consumption of low glycemic index carbohydrate meals [PDF]

, 2005
The present study examined the effects of the glycemic index (GI) of post-exercise carbohydrate (CHO) intake on endurance capacity and the metabolic responses during exercise the following day. Nine active males participated in two trials in a randomised
Oram, Chris, Williams, Clyde, Stevenson, Emma, McComb, Gareth   +3 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source