Results 91 to 100 of about 35,491 (233)

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Quantifying the metabolic-inflammatory axis: synergistic value of TyG index and FAI in assessing CAD risk among MAFLD patients

Frontiers in Endocrinology
BackgroundThis study evaluated coronary inflammation and insulin resistance (IR) using pericoronary fat attenuation index (FAI) and triglyceride-glucose (TyG) index, and assessed their associations with coronary heart disease (CHD) and functional ...
Xiaolong Bai, Xiaolong Bai, Zhijun Wang, Ziyi Cao, Junping Zhen, Junping Zhen   +5 more
doaj   +1 more source

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Eutectozymes as Soft Hybrid Materials for Advanced Biocatalysis

Advanced Materials, EarlyView.
Eutectozymes are sustainable hybrid materials that embed a GOx–HRP cascade within hydrophobic eutectogels featuring a dual supramolecular–covalent network. This architecture preserves native enzyme structure and stability, enables efficient heterogeneous biocatalysis in aqueous media, and positions eutectogels as robust platforms for next‐generation ...
Manuel Eduardo Martinez Cartagena, Lucia Suarez, Aitor Ontoria, Francisca J. Benitez, Elixabete Rezabal, María Soledad Orellano, Marcelo Calderón, Cristián Huck‐Iriart, Agustin S. Picco, Matias L. Picchio, Ana Beloqui   +10 more
wiley   +1 more source

Abdominal CT-derived metabolic phenotypes are associated with the MRI-derived brain age gap in women

Frontiers in Aging Neuroscience
BackgroundMetabolic dysfunction is increasingly recognized as a systemic contributor to adverse brain aging; however, conventional clinical markers may not fully capture tissue-level variations in liver attenuation, abdominal adiposity, and muscle ...
Chongwon Pae, Chongwon Pae, Minchul Kim, Inpyeong Hwang, Inpyeong Hwang, Joon Ho Moon, Joon Ho Moon, Kyu Sung Choi, Kyu Sung Choi, Kyu Sung Choi   +9 more
doaj   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

Advanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase, Varsha C. Pujari, Akash V. Fulari, Sunil M. Patange, Sean Li, Danyang Wang, Sagar E. Shirsath   +6 more
wiley   +1 more source

Intrinsically Stretchable Piezoelectric Nanocomposites for Artificial Ultrasonic Sensory Synapse

Advanced Materials, EarlyView.
Applying ultrasonic stimulations to a soft‐stretchable underwater piezoelectric sensor based on the soft‐stretchable nanocomposite from the thermal cross‐linking between the ─C─F group of P(VDF‐TrFE) and the ─NH2 group of (PEG‐diamine) with incorporating amine‐terminated BTO@APTES nanofillers on the soft PDMS substrates generated high piezoelectric ...
Trung Dieu Do, Tran Quang Trung, Priyanuj Bhuyan, Minh Chien Nguyen, Que Thi Nguyen, Namjun Jo, Yeonsu Kim, Thanh Duy Cam Ha, Myung‐Gil Kim, Sungjune Park, Woo Jong Yu, Nae‐Eung Lee   +11 more
wiley   +1 more source

Deep‐Tissue Light Generation via Whispering Gallery Mode Lasing From a Commercial Nylon Fiber for Biomedical Applications

Advanced Materials Technologies, EarlyView.
A dyed nylon fiber is implemented inside the scattering phantom and skin tissue. The deep‐tissue light generation via whispering gallery mode lasing is demonstrated, achieving a depth of >50 times transport mean free path in scattering phantom and 3 mm beneath skin.
Dongqin Ni, Florian Klämpfl, Fernando Lahoz, Michael Schmidt, Martin Hohmann   +4 more
wiley   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Associations of triglyceride glucose index and atherogenic index of plasma with plaque, inflammation, flow, and functional ischemia assessed by cardiovascular computed tomography imaging in hypertensive patients: a study of different glucose metabolism status

Annals of Medicine
Background The triglyceride glucose (TyG) index and atherogenic index of plasma (AIP) are indicators of insulin resistanceand atherosclerosis, respectively. Nevertheless, their relationship with coronary plaque, inflammation, flow and functional ischemia
Shuting Wang, Na Li, Hong Pan, Jinquan Bai, Zhenzhou Shi, Tong Zhang   +5 more
doaj   +1 more source