Results 91 to 100 of about 1,266,176 (354)

Longitudinal association of adiposity with wheezing and atopy at 22 years: the 1993 Birth Cohort, Pelotas, Brazil

Journal of Asthma and Allergy, 2018
Ana Maria Baptista Menezes,1 Paula Duarte de Oliveira,1 Cauane Blumenberg,1 Efrain Sanchez-Angarita,2 Gloria Isabel Niño-Cruz,1 Ignacio Zabert,3 Janaina Calu Costa,1 Luiza Isnardi Cardoso Ricardo,1 Rafaela Costa Martins,1 Fernando César ...
Menezes AMB, Oliveira PD, Blumenberg C, Sanchez-Angarita E, Niño-Cruz GI, Zabert I, Costa JC, Ricardo LIC, Martins RC, Wehrmeister FC   +9 more
doaj  

Inflating Fat Bubbles in Clusters of Galaxies by Precessing Massive Slow Jets

, 2008
We conduct hydrodynamical numerical simulations and find that precessing massive slow jets can inflate fat bubbles, i.e., more or less spherical bubbles, that are attached to the center of clusters of galaxies.
Assaf Sternberg, Morita U., Noam Soker, Reynolds C. S., Vrtilek J. M.   +4 more
core   +1 more source

Measurements of body fat is associated with markers of inflammation, insulin resistance and lipid levels in both overweight and in lean, healthy subjects [PDF]

, 2012
Background & aims: Low-grade inflammation is associated with fat mass in overweight. Whether this association exists in lean persons is unknown. Aims were to investigate associations between anthropometric measures of fat distribution and fat mass (% and
Bye, Asta, Dahlman, Ingrid, Hjermstad, Marianne J., Holven, Kirsten B., Iversen, Per Ole, Narverud, Ingunn, Telle-Hansen, Vibeke H., Ulven, Stine M., Wesseltoft-Rao, Nima   +8 more
core   +4 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Impact of exercise-nutritional state interactions in patients with type 2 diabetes

, 2020
Introduction This study examines the role of nutritional status during exercise training in patients with type 2 diabetes mellitus by investigating the effect of endurance-type exercise training in the fasted versus the fed state on clinical outcome ...
Calders, Patrick, Celie, Bert, Dendale, Paul, Hansen, Dominique, Lapauw, Bruno, Stevens, An, van Loon, Luc JC, Vandenabeele, Frank, Verboven, Kenneth, Wens, Inez   +9 more
core   +1 more source

Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue [PDF]

, 2018
Aims/hypothesis: The association between increased (visceral) fat mass, insulin resistance and type 2 diabetes mellitus is well known. Yet, it is unclear whether the mere increase in intra-abdominal fat mass, or rather functional alterations in fat ...
Alessandra G. Pellegrino, Alessandra G. Pellegrino, Alessandro Bonaccorso, Flavio Cannavò, Letizia Spampinato, Sonia Calvari   +5 more
core   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Body Composition in Swiss Elite Wheelchair Athletes

Frontiers in Nutrition, 2020
The aim of this study was to retrospectively interpret body composition in various wheelchair athletes. In total, 69 athletes (mean ± standard deviation; age 33 ± 11 years; body mass 65.1 ± 14.8 kg; height 169.9 ± 14.9 cm and time since injury 19 ± 11 ...
Joelle Leonie Flueck
doaj   +1 more source

Changes in Insulin-Like Growth Factor-I and -II Associated with Fat but not Lean Mass in Early Old Age [PDF]

, 2015
Objective: To test the hypothesis that insulin-like growth factors-I and II (IGF-I and II) decline during late midlife and that greater declines are related to higher fat mass and lower lean mass.
Adams, Andersen, Ben-Shlomo, Benn, Berryman, Bidlingmaier, Birnie, Burgers, Chaston, Cooper, Crowe, Crowe, Firth, Flegal, Harris, Holly, Holt, Huang, Jakobsdottir, Junnila, Klinger, Kuh, Kuk, Livingstone, Lukanova, Martin, Nindl, Nindl, Nindl, O'Connor, Parekh, Rejeski, Rodriguez, Sandhu, Schrager, Seck, Soubry, Vestergaard, Wolfe, Ye   +39 more
core   +2 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source