Results 211 to 220 of about 595,756 (311)

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Sedentary lifestyle is independently associated with higher fat mass index regardless of physical activity level in patients with coronary artery disease. [PDF]

BMC Cardiovasc Disord
Novaković M, Salgueiro D, Lemos Pires M, Borges M, Sá G, Fras Z, Pinto FJ, Abreu A, Pinto R.   +8 more
europepmc   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Association Between Relative Fat Mass and Cardiometabolic Disease: Age-Stratified Analysis in Young and Middle-Aged Versus Older Adults. [PDF]

Rev Cardiovasc Med
Li T, Xie X, Jin Z, Nan J, Han J, Yin L.
europepmc   +1 more source

Correlation of skeletal muscle mass and visceral fat area with hyperuricemia in male adolescents

Wen Mao, Qing Li, Guangjun Zhu, Linyan Cheng, Donglian Wang, Bo Shen, Yu Zheng   +6 more
openalex   +1 more source

Hemifacial mass with extensive intralesional ossification and fat

, 2012
Sumeet G. Dua, A V Kulkarni, Sunita Kulkarni, N. S. Shetty, Tanuja Shet   +4 more
openalex   +2 more sources

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Relative Fat Mass as an Estimator of Abdominal Adiposity in Youth Across the BMI Spectrum from Normal Weight to Obesity. [PDF]

Pediatr Obes
Cho W, Kim JY, Arslanian S.
europepmc   +1 more source

The Fat-Mass and Obesity-Associated (FTO) gene, physical activity, and risk of incident cardiovascular events in white women

, 2010
Tariq Ahmad, Daniel I. Chasman, Samia Mora, Guillaume Paré, Nancy R. Cook, Julie E. Buring, Paul M. Ridker, I‐Min Lee   +7 more
openalex   +2 more sources

2‐line Ferrihydrite Enhance Microbial Synthesis of Plant Biostimulants in Composted Biosolid by Regulating Phyla Pseudomonadota and Actinomycetota

Advanced Science, EarlyView.
This study explores how iron and manganese oxides transform sewage sludge into plant biostimulants during composting. Non‐targeted identification reveals the main species of plant biostimulants. Metagenomic analysis reveals that 2‐line ferrihydrite specifically enriches microbial genes for biosynthesis, boosting plant‐growth promoters.
Yu Zhang, Ziwei Zhang, Zexu Chen, Boyuan Yang, Siying Cai, Jun Chen, Jianhua Guo, Weijun Zhang   +7 more
wiley   +1 more source