Surplus fat rapidly increases fat oxidation and insulin resistance in lipodystrophic mice
Objective: Surplus dietary fat cannot be converted into other macronutrient forms or excreted, so has to be stored or oxidized. Healthy mammals store excess energy in the form of triacylgycerol (TAG) in lipid droplets within adipocytes rather than ...
Amandine Girousse +7 more
doaj +3 more sources
Hypoxia, Oxidative Stress and Fat [PDF]
Metabolic disturbances in white adipose tissue in obese individuals contribute to the pathogenesis of insulin resistance and the development of type 2 diabetes mellitus. Impaired insulin action in adipocytes is associated with elevated lipolysis and increased free fatty acids leading to ectopic fat deposition in liver and skeletal muscle.
Nikolaus Netzer +5 more
openaire +3 more sources
Pre-exercise meal on oxidation of energy substrates during maximal exercise test in non-trained individuals [PDF]
Objective: This study aimed to compare the influence of a high carbohydrate meal versus high-fat meal on the oxidation of substrates during an exercise incremental test.
Lucas Ribeiro da Silva +4 more
doaj +1 more source
Role of Solid Fat Content in Oxidative Stability of Low-Moisture Cracker Systems
Lipid oxidation is a major pathway for the chemical deterioration of low-moisture foods. Little is known about how the physical properties of the fat used in crackers impact lipid oxidation kinetics.
Thanh Phuong Vu +5 more
doaj +1 more source
Dietary fat oxidation as a function of body fat [PDF]
It is hypothesized that low dietary fat oxidation makes subjects prone to weight gain.The aim of the study was to determine dietary fat oxidation in normal, overweight, and obese subjects.The subjects were 38 women and 18 men with a mean (+/-SD) age of 30+/-12 y and a body mass index (in kg/m2) of 25+/-4 (range: 18-39).
Westerterp, K.R. +4 more
openaire +3 more sources
Studies have revealed that time-restricted feeding affects the fat oxidation rate; however, its effects on the fat oxidation rate and hyperlipidemia following high-fat meals are unclear.
Chih-Hui Chiu +6 more
doaj +1 more source
Lipolytic Markers, Insulin and Resting Fat Oxidation are Associated with Maximal Fat Oxidation [PDF]
The maximal capacity to oxidize fat during exercise (MFO) is associated with 24-h fat balance and insulin sensitivity. Understanding factors that influence MFO could have implications for metabolic health. We investigated relationships between selected plasma metabolites, hormones and overnight-fasted resting fat oxidation rates (Resting), with MFO ...
S L, Robinson +3 more
openaire +2 more sources
A feedback loop governs the relationship between lipid metabolism and longevity
The relationship between lipid metabolism and longevity remains unclear. Although fat oxidation is essential for weight loss, whether it remains beneficial when sustained for long periods, and the extent to which it may attenuate or augment lifespan ...
Nicole K Littlejohn +3 more
doaj +1 more source
Fat content and nitrite-curing influence the formation of oxidation products and NOC-specific DNA adducts during in vitro digestion of meat. [PDF]
The effects of fat content and nitrite-curing of pork were investigated on the formation of cytotoxic and genotoxic lipid oxidation products (malondialdehyde, 4-hydroxy-2-nonenal, volatile simple aldehydes), protein oxidation products (protein carbonyl ...
Thomas Van Hecke +5 more
doaj +1 more source
Diurnal variations of brown fat thermogenesis and fat oxidation in humans [PDF]
Abstract Background/objectives Disturbed circadian rhythm is associated with an increased risk of obesity and metabolic disorders. Brown adipose tissue (BAT) is a site of nonshivering thermogenesis (NST) and plays a role in regulating whole-body energy expenditure (EE), substrate metabolism, and body fatness.
Mami Matsushita +7 more
openaire +2 more sources

