Results 51 to 60 of about 1,029,119 (281)

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

The Indications and Potential Complications of Supplementing with Fat-Soluble Vitamins [PDF]

, 2022
There is a seemingly infinite list of available formations of over-the-counter supplements, including vitamins. According to Grand View Research, the nutritional supplement industry has grown in popularity in recent years, increasing its worth to an ...
Thielges, Krista
core   +1 more source

A Dual-Mode CE–MS/MS Strategy for Simultaneous Determination of Water- and Fat-Soluble Vitamins in Juices, Milk, and Yogurt

Bulletin of Pharmaceutical Sciences. Assiut University
Measuring vitamins in food is an essential step in verifying nutritional claims and monitoring quality since juices and dairy products vary in polarity, stability, and matrix effects.
Sura Ahmed, Hayfaa Atawy, Reem Noman, Maytham Bakr, Mohammed Saleh, Jamil Saleh   +5 more
doaj   +1 more source

Identification of fat-soluble vitamins deficiency using artificial neural network [PDF]

, 2020
The fat-soluble vitamins (A, D, E, K) deficiency remain frequent universally and may have consequential adverse resultants and causing slow appearance symptoms gradually and intensify over time.
Cynthia Hayat, Tandipuang, Frahselia, Hayat, Cynthia, Frahselia Tandipuang, Sagala, Noviyanti, Noviyanti Sagala   +5 more
core   +1 more source

Super‐Multiplexed Label‐Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation

Advanced Science, EarlyView.
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li, Xia Chen, Yujuan Qi, Chen Qiao, Qiuru Huang, Dan Zhao, Weiyi Qian, Li Di, Yi Shi, Xiangqi Hu, Yueyue Shao, Kehan Wang, Zhiyu Tang‐Yang, Hanzhi Zang, Yuwen Du, Anran Dong, Jinxiong Feng, Jiayun Chen, Ying Zheng, Xiaofang Tan, Xiaoyu Zhao, Zhonghua Shi, Bo Zheng, Jun Yu   +23 more
wiley   +1 more source

Fat-soluble vitamins: XX. A modified technique for the determination of vitamin A

, 1924
FAT-SOLUBLE VITAMINS: XX. A MODIFIED TECHNIQUE FOR THE DETERMINATION OF VITAMIN A Fat-soluble vitamins: XX. A modified technique for the determination of vitamin A (62) (-
Steenbock, H. Mariana T. Nelson Archie Black
core   +2 more sources

Hydrosoluble and Liposoluble Vitamins: New Perspectives through ADMET Analysis

Medicina, 2021
Background and Objectives: The present study demonstrates that apart from the well-known toxicity of liposoluble vitamins, some hydrosoluble vitamins may also exert toxicity; thus, routine supplementation with vitamins or ingestion of fortified foods ...
Mirela Nicolov, Mioara Cocora, Valentina Buda, Corina Danciu, Adina Octavia Duse, Claudia Watz, Florin Borcan   +6 more
doaj   +1 more source

The MoSR‐MoDde1 Regulatory Axis: A Novel Determinant of DMI Sensitivity and a Target for Sustainable Rice Blast Control

Advanced Science, EarlyView.
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng, Wen‐Kai Wei, Meng‐Yao Wu, Min‐Zheng Cai, Yu‐Fu Wang, Li Zhao, Shuai Meng, Liang‐Fen Yin, Guido Schnabel, Wei‐Xiao Yin, Chao‐Xi Luo   +10 more
wiley   +1 more source

Improving the Physicochemical Properties, Organic Acids, Amino Acids, Volatile Organic Compounds, and Metabolites of Laohan Melon Juice Through Fermentation With Different Lactic Acid Bacteria

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Fermentation with lactic acid bacteria could improve amino acids, volatile organic compounds (VOCs), and nonvolatile metabolites of Laohan melon juice (LMJ), which provides theoretical guidance for the development of Laohan melon beverage and advances knowledge of the metabolic mechanisms of VOCs in LMJ.
Yun Xie, Sihan Hou, Mingdong Tan, Jianqiao Jiang, Yue Hu, Yiwen Chen, Yongkang Li, Miao Cui, Jianming Niu, Weidong Cheng, Xilei Pu, Yuyun He, Feifei Gao   +12 more
wiley   +1 more source

Fermentation Potentials of Baobab Pulp Extract in Soy Yoghurt Production

AgriFood: Journal of Agricultural Products for Food, EarlyView.
The research work was about the importance of sourcing for alternative inoculants to replace the main inoculants regularly used for yoghurt production. The search for baobab pulp extract as replacement yielded result, as soy yoghurt was successfully produced.
Adegbola Oladele Dauda, Nahim Mokolade Adeagbo, Quadri Idowu Akinremi, Taofiqat Damilola Maiyaki, Adedamola Israel Abioye, Zulfiqoh Tolani AbdulAkeem, Damilare Johnson Folaranmi   +6 more
wiley   +1 more source