Results 41 to 50 of about 2,131,862 (310)
“Saving the crippled foot” – a study on diabetic foot ulcers and its salvage using flap surgeries
Journal of the Foot & AnkleObjective: Emphasize the importance of a comprehensive and aggressive management with surgical debridement and flap-based reconstruction of defects in patients with diabetic foot ulcers (Ganga Class 3), and in turn, focusing on limb salvage.
Akhil Xavier Joseph +4 more
doaj +1 more source
National Journal of Physiology, Pharmacy and Pharmacology, 2021 Background: Me-too drugs are usually defined as drugs with a similar chemical structure or the identical mechanism of action as the drugs that are previously in the market.
Chandralekha N +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Patients’ Attitudes Toward Care by Male Nurses in a Tertiary Care Center in Mangalore
Social MedicineBackground. Nursing is a profession that combines technical expertise with empathy to alleviate suffering and promote well-being. Although the number of male nurses has been increasing, the field is still widely regarded as female-dominated, a ...
Jooli Mathew +5 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Prevalence of Clostridium Difficile Among Paediatric Patients in a Tertiary Care Hospital, Coastal Karnataka, South India [PDF]
Journal of Clinical and Diagnostic Research, 2015 Introduction: The study was intended to analyse the burden of Clostridium difficile (C. difficile) and associated intestinal pathogens from children with diarrhoea who were hospitalized in a tertiary care teaching hospital of South India.
Sherin Justin +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Online Journal of Health & Allied Sciences, 2014 Primary squamous cell carcinoma of the endometrium is exceedingly rare. We report a case of 52 years old postmenopausal woman who presented with pelvic pain of four months duration. Gynecologic examination revealed a normal cervix.
Pailoor K +5 more
doaj
Melioidosis with a Pericardial Effusion, which Relapsed as a Chest Wall Abscess: A Rare Presentation [PDF]
Journal of Clinical and Diagnostic Research, 2013 Melioidosis, which is caused by a soil saprophyte, Burkholderia pseudomallei, is most prevalent in the south–west coast of India. Although it is frequently seen in immunocompromised patients, melioidosis can occur in apparently normal individuals ...
Rashmi Teresa Mathai K. +4 more
doaj +1 more source