Results 61 to 70 of about 2,131,862 (310)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Role of modified haematological sepsis score and red cell distribution width in early diagnosis of neonatal sepsis [PDF]

Al Ameen Journal of Medical Sciences
Background: Neonatal sepsis is one of the leading causes of morbidity and mortality in neonates. The subtle clinical signs may sometimes go unnoticed. Blood culture is considered to be the gold standard, however it is time consuming.
Sweta Shanbhag, Rashmi Alva, Sudhir Prabhu H   +2 more
doaj  

Awareness of Periconceptional use of Folic Acid to Prevent Neural Tube Defects in Young Females of Dakshina Kannada Region, India: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Neural Tube Defects (NTDs) are one of the common congenital anomalies leading to miscarriages and serious disabilities in newborns. NTDs are the second most common type of birth defects.
Joseph Paul Arnold, Varsha Shenoy, Prathima Prabhu, Deepshreya Sheron   +3 more
doaj   +1 more source

Utilitarian Reasoning in Nazi Medical Policy: Some Preliminary Investigations [PDF]

, 1975
Roll 102b. Walsh Hall #2. Image 15 of 47. (29 January, 1954) [PHO 1.102b.15]The Boleslaus Lukaszewski (Father Luke) Photographs contain more than 28,000 images of Saint Louis University people, activities, and events between 1951 and 1970.
LaChat, Michael R.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Review of \u3cem\u3eWhen the Devil Knocks: The Congo Tradition and the Politics of Blackness in Twentieth-Century Panama\u3c/em\u3e [PDF]

, 2016
Roll 91. New York - SLU at St. John's. Image 3 of 20. (28 December, 1953) [PHO 1.91.3]The Boleslaus Lukaszewski (Father Luke) Photographs contain more than 28,000 images of Saint Louis Univrsity people, activities, and events between 1951 and 1970.
Donoghue, Michael
core   +1 more source

FAST FATHERS FATHER MORE [PDF]

Journal of Experimental Biology, 2007
![Figure][1] It is widely assumed that in the animal kingdom faster means better. Speed often implies that an animal is better at escaping from predators, and capturing prey. Indeed, a growing number of studies are linking whole-organism performance traits, such as locomotor speed, to ...
openaire   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Book Review of \u3cem\u3ePsychoanalysis Today\u3c/em\u3e by Agostino Gemelli, Translated by John Chapin and Salvator Attanasia [PDF]

, 1952
Roll 28. Fr. B.T. Lukaszewski, S.J. Image 8 of 20. (December 1952) [PHO 1.28.22]The Boleslaus Lukaszewski (Father Luke) Photographs contain more than 28,000 images of Saint Louis University people, activities, and events between 1951 and 1970.
Gannon, Timothy J.
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source