Results 31 to 40 of about 174,013 (259)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala +8 more
wiley +1 more source
Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas +3 more
wiley +1 more source
High Temperature Materials and Processes, 2020 In this paper, the damage accumulation and life prediction in fiber-reinforced ceramic-matrix composites (CMCs) subjected to thermomechanical fatigue (TMF) loading are investigated.
Li Longbiao
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Fatigue Design Research on Notch–Stud Connectors of Timber–Concrete Composite Structures
BuildingsTo investigate the mechanical behavior and damage mechanism of notch–stud connectors in timber–concrete composites under fatigue loading, fifteen push-out specimens in five groups were designed with load cycles as the key variable.
Zuen Zheng, Shuai Yuan, Guojing He
doaj +1 more source
Nonlinear Fatigue Damage Accumulation
Fatigue of Aircraft Structures, 2015 One important element of any computational fatigue analysis is the adoption of a hypothesis of fatigue damage accumulation. The most commonly used is the hypothesis of linear accumulation of fatigue damage called the Palmgren-Miner hypothesis.
Dębski Daniel Krzysztof
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Metals, 2023 A7N01P-T4 aluminum alloy plates for high-speed trains will experience a certain amount of fatigue damage under alternating loads. Three groups of samples, P0 (no fatigue damage), P1 (loading stress 30 MPa), and P2 (loading stress 70 MPa), were created ...
Wenjing Chen +5 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source