Results 61 to 70 of about 342,663 (257)
The effect of the number of response cycles on the behaviour of reinforced concrete elements subject to cyclic loading [PDF]
, 2012 The development of damage in reinforced concrete (RC) structures is a cumulative process. Some damage indices used to quantify damage make use of the number of response cycles as an Engineering Demand Parameter (EDP) relating with damage development ...
Borg, R. C., Rossetto, T., Varum, H.
core +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
The relationship between observed fatigue damage and life estimation models [PDF]
Observations of the surface of laboratory specimens subjected to axial and torsional fatigue loadings has resulted in the identification of three damage fatigue phenomena: crack nucleation, shear crack growth, and tensile crack growth.
Kurath, Peter, Socie, Darrell F.
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A fatigue damage meso-model for fiber-reinforced composites with stress ratio effect [PDF]
, 2016 This work presents a fatigue damage meso-model for fiber-reinforced plastic composites, in which the effect of stress ratios on the off-axis fatigue behavior is taken into account.
Scarpa, Fabrizio +3 more
core +2 more sources
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source
Applied SciencesConcrete linings containing cold joint defects may crack or detach under the aerodynamic fatigue loading generated by high-speed train operation, which posing a serious threat to the normal operation of high-speed trains.
He-Lin Fu +4 more
doaj +1 more source
Low-velocity impact response of friction riveted joints for aircraft application
Materials & Design, 2020 In this paper, the sensitivity of carbon fiber reinforced polyether-ether-ketone (CF-PEEK) friction riveted joints to impact damage was assessed as well as the damage propagation during fatigue and quasi-static mechanical testing.
N.Z. Borba +4 more
doaj +1 more source
Observations of fatigue crack nucleation and early growth are presented. The state of stress/strain was shown to play a significant role in this process.
Socie, Darrell
core +1 more source
A probabilistic high cycle fatigue model applied to cast Al-Si alloys [PDF]
, 2013 In this work, the high cycle fatigue behavior of cast hypo-eutectic Al-Si alloys is investigated. It is observed that two different coexisting fatigue initiation mechanisms can occur in these materials depending on the presence of different ...
AUGUSTINS, Louis +3 more
core +3 more sources