Results 51 to 60 of about 1,070,454 (316)

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Fatigue life of hot mix asphalt mixtures [PDF]

open access: yes, 2011
Fatigue cracking is one of the major types of distress in asphalt concrete pavements. Under the action of repeated vehicular loading, the asphalt concrete deteriorates and eventually results in fatigue cracking.
Abdulridha, Ammar Ali
core  

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein   +13 more
wiley   +1 more source

A new fatigue equation for asphalt mixtures considering loading sequence effects

open access: yesCase Studies in Construction Materials
The fatigue life of asphalt mixture has been found to significantly depend on loading sequences. However, the widely used traditional linear fatigue equations are difficult to determine the fatigue life of asphalt mixture subjected to different loading ...
Chenze Fang   +5 more
doaj   +1 more source

Failure behaviour of preloaded API line pipe threaded connections [PDF]

open access: yes, 2011
This paper reports on numerical and experimental work concerning the fatigue behaviour and sealing capacity of threaded pipe connections (1” API Line Pipe). Numerical simulations are performed using Abaqus® in combination with ThreadGen©.
De Baets, Patrick   +5 more
core   +1 more source

Barriers to Investment Abroad as Tools of Payments Policy [PDF]

open access: yes, 1969
The thesis examines the fatigue life of weld ends, where very little usable research previously has been conducted, and often the weld ends are the critical parts of the weld.
Furth, J. Herbert
core   +3 more sources

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Evaluation of fatigue life of asphalt binders using the time sweep and linear amplitude sweep tests: A literature review

open access: yesJournal of Traffic and Transportation Engineering (English ed. Online)
Asphalt binders play a crucial role in the fatigue cracking resistance of asphalt pavement, making the characterization of their fatigue life increasingly important. To evaluate the fatigue life of asphalt binders, two tests have been developed: the time
Mohammed Nouali, Anne Dony, Alan Carter
doaj   +1 more source

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