Results 181 to 190 of about 11,054 (291)

Battle of the giants: KDIGO vs. Cochrane - who is the winner in the fight for blood pressure targets in chronic kidney disease? [PDF]

J Bras Nefrol
Rodrigues CIS, Moura AF, Bezerra R.
europepmc   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Prevalence of venous thromboembolism and associated factors in COVID-19 patients at a provincial public hospital in southern Brazil. [PDF]

J Vasc Bras
Dutra BV, Dutra LV, Weber HL, Reinheimer MO, Pezzi M, Macalossi GT, Bonatto S, Dutra CF.   +7 more
europepmc   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Intestinal microbiota profile and inflammation in patients undergoing hemodialysis: a comparison between the Southern and Southeastern regions of Brazil. [PDF]

J Bras Nefrol
Paiva BR, Schultz J, Modolon F, Brito JS, Ribeiro-Alves M, Rosado AS, Cardozo LFMF, Mafra D.   +7 more
europepmc   +1 more source

Retificação trifásica com alto fator de potência usando uma conexão especial de transformadores para a redução de harmônicas da corrente [PDF]

, 1997
Munoz B., Carlos Amable
core  

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

SMOKING IMPACTS HELICOBACTER PYLORI ERADICATION: RESULTS FROM A BRAZILIAN UNIVERSITY HOSPITAL. [PDF]

Arq Gastroenterol
Fonte AACFRD, Cunha-Silva M, Rondon MVSDS, Santos CRD, Hara NH, Nagasako CK.   +5 more
europepmc   +1 more source

Tempo Próprio Efetivo em Circuitos Elétricos e Eletrônicos: Critério Energia--Causal, Operador \(K\), Fator \(G(K)\) e Protocolos de Projeto

Este trabalho apresenta a versão operacional, em engenharia elétrica e eletrônica, do formalismo de tempo próprio efetivo derivado na Parte I. A tese central é que o tempo próprio de uma excitação circuital não deve ser identificado com atrasode grupo, fase, dispersão, tempo de ...
openaire   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

Advanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang, Tan Wei, Jiahang Wu, Chuixu Lin, Dongbo Zhu, Yanhui Li, Shuting Shi, Shishun Huang, Leiming Jiang, Hongzhi Wang, Meiqi Song, Pengfei Gao, Xu Wu, Mingjian Fan, Chaofeng Wei, Qian Wang, Lihui Qu, Zhigang Wang   +17 more
wiley   +1 more source