Results 141 to 150 of about 189,904 (253)

Comparing Soy and Milk Protein Regulation of Hepatic Omega-3 Fatty Acid Biosynthesis. [PDF]

open access: yesFASEB J
Gonzalez-Soto M   +9 more
europepmc   +1 more source

THE BIOSYNTHESIS OF RADIOACTIVE FATTY ACIDS AND CHOLESTEROL

open access: yesJournal of Biological Chemistry, 1950
R O, BRADY, S, GURIN
openaire   +2 more sources

Fibrillarin Resists Cellular Senescence Via SIRT1‐Dependent Nicotinamide Metabolism and Its Inhibition Sensitizes Senolytic Therapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
FBL directly binds to and stabilizes SIRT1 by blocking its ubiquitin‐proteasome degradation, thereby sustaining nicotinamide metabolism and redox homeostasis to counteract cellular senescence in ESCC. Genetic and pharmacological suppression of FBL sensitizes tumor cells to senolytic therapy.
Xing Jin   +9 more
wiley   +1 more source

Investigating the potential of dietary iron supplementation to enhance long-chain polyunsaturated fatty acid biosynthesis in Hediste diversicolor. [PDF]

open access: yesSci Rep
Villena-Rodríguez A   +8 more
europepmc   +1 more source

ON THE REGULATION OF FATTY ACID BIOSYNTHESIS BY LIPOGENIN [PDF]

open access: yesProceedings of the National Academy of Sciences, 1958
G N, Catravas, H S, Anker
openaire   +2 more sources

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

open access: yesAdvanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu   +17 more
wiley   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

open access: yesAdvanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv   +16 more
wiley   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu   +12 more
wiley   +1 more source

Physiological Effects of Water Salinity on Metabolism and Fatty Acid Biosynthesis in the Model Fish <i>Fundulus heteroclitus</i>. [PDF]

open access: yesAnimals (Basel)
Torres-Rodríguez M   +4 more
europepmc   +1 more source

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