Results 151 to 160 of about 2,963,117 (406)

Non-alcoholic fatty liver disease in children and young adults is associated with increased long-term mortality

open access: green, 2021
Tracey G. Simon   +6 more
openalex   +2 more sources

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals with Type 2 Diabetes

open access: yesArthritis Care &Research, Accepted Article.
Objective Knee osteoarthritis (OA) commonly affects individuals with Type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King   +10 more
wiley   +1 more source

Associations of Sleep and Shift Work with Osteoarthritis Risk

open access: yesArthritis Care &Research, Accepted Article.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships between circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000‐person cohort, we evaluated associations between sleep duration, sleeplessness/insomnia, and ...
Elizabeth L. Yanik   +5 more
wiley   +1 more source

The Tumor-Associated Neutrophils-Related Signatures Predict Prognosis and Indicate Immune Landscape in Colorectal Carcinoma

open access: yesMediators of Inflammation
Conclusions: This study comprehensively analyzed the role of TANs in CRC progression and developed a prognostic model based on TANs-related genes, which holds significant potential for predicting prognosis and immunotherapy outcomes in CRC patients.
Ying Wang   +5 more
doaj   +1 more source

Ability of soluble TREM2 and PRO-C3 as biomarkers to predict changes in MASLD activity

open access: yesJHEP Reports
Background & Aims: Diet and weight loss remain the primary treatment for most patients with metabolic dysfunction-associated fatty liver disease (MASLD), with one recent drug therapy approved for severe cases.
Charlotte Wilhelmina Wernberg   +16 more
doaj   +1 more source

An ANGPTL4-ceramide-protein kinase Cζ axis mediates chronic glucocorticoid exposure-induced hepatic steatosis and hypertriglyceridemia in mice. [PDF]

open access: yes, 2019
Chronic or excess glucocorticoid exposure causes lipid disorders such as hypertriglyceridemia and hepatic steatosis. Angptl4 (angiopoietin-like 4), a primary target gene of the glucocorticoid receptor in hepatocytes and adipocytes, is required for ...
Cheang, Rachel T   +11 more
core  

Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]

open access: yes, 2019
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence   +2 more
core   +2 more sources

Probiotic Bifidobacterium Lactis V9 attenuates hepatic steatosis and inflammation in rats with non-alcoholic fatty liver disease [PDF]

open access: gold, 2020
Yan Yan   +7 more
openalex   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

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