Results 71 to 80 of about 2,461,573 (347)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Reliability and fault tolerance modelling of multiprocessor systems [PDF]

, 1989
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Reliability evaluation by analytic modelling constitute an important issue of designing a reliable multiprocessor system.
Valdivia, Roberto Abraham
core  

Enhancing the Fault Tolerance of a Multi-Layered IoT Network through Rectangular and Interstitial Mesh in the Gateway Layer

Journal of Sensor and Actuator Networks, 2023
Most IoT systems designed for the implementation of mission-critical systems are multi-layered. Much of the computing is done in the service and gateway layers. The gateway layer connects the internal section of the IoT to the cloud through the Internet.
Sastry Kodanda Rama Jammalamadaka, Bhupati Chokara, Sasi Bhanu Jammalamadaka, Balakrishna Kamesh Duvvuri, Rajarao Budaraju   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Bayesian Network Based Fault Tolerance in Distributed Sensor Networks

Journal of Telecommunications and Information Technology, 2014
A Distributed Sensor Network (DSN) consists of a set of sensors that are interconnected by a communication network. DSN is capable of acquiring and processing signals, communicating, and performing simple computational tasks. Such sensors can detect and
B. Bhajantri Lokesh, N. Nalini
doaj   +1 more source

Programming Language Constructs Supporting Fault Tolerance [PDF]

Leibniz Transactions on Embedded Systems, 2016
In order to render software viable for highly safety-critical applications, we describe how to incorporate fault tolerance mechanisms into the real-time programming language PEARL.
Houben, Christina, Houben, Sebastian
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Fault-tolerant geometric spanners [PDF]

Proceedings of the nineteenth annual symposium on Computational geometry, 2003
We present two new results about vertex and edge fault-tolerant spanners in Euclidean spaces. We describe the first construction of vertex and edge fault-tolerant spanners having optimal bounds for maximum degree and total cost. We present a greedy algorithm that for any \(t > 1\) and any non-negative integer \(k\), constructs a \(k\)-fault-tolerant ...
Artur Czumaj, Hairong Zhao
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Software implemented fault tolerance for microprocessor controllers: fault tolerance for microprocessor controllers [PDF]

, 1992
It is generally accepted that transient faults are a major cause of failure in micro processor systems. Industrial controllers with embedded microprocessors are particularly at risk from this type of failure because their working environments are prone ...
Wingate, Guy A.S.
core