Results 31 to 40 of about 31,328 (309)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Fault tolerance in computational grids: perspectives, challenges, and issues
SpringerPlus, 2016 Computational grids are established with the intention of providing shared access to hardware and software based resources with special reference to increased computational capabilities. Fault tolerance is one of the most important issues faced by the computational grids.
Haider, Sajjad, Nazir, Babar
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
HARNESS fault tolerant MPI design, usage and performance issues [PDF]
Future Generation Computer Systems, 2002 Initial versions of MPI were designed to work efficiently on multi-processors which had very little job control and thus static process models. Subsequently forcing them to support a dynamic process model suitable for use on clusters or distributed systems would have reduced their performance.
Fagg, Graham E., Dongarra, Jack J.
openaire +2 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
IEEE Access, 2018 Energy saving and system reliability are two crucial issues for designing modern multiprocessor systems. There has been reliability-aware power management with dynamic voltage-frequency scaling (DVFS) schemes in recent studies.
Kai Huang +6 more
doaj +1 more source
Functional Safety Analysis and Design of Sensors in Robot Joint Drive System
Machines, 2022 The reliable operation of the sensors of robot joint drive systems (RJDs) is a key factor in ensuring the safety of equipment and personnel. Over the years, additional safety-related systems have been designed to prevent safety incidents caused by robot ...
Lingyu Chen +3 more
doaj +1 more source
Implications of fault current limitation for electrical distribution networks
, 2010 This paper explores the potential future need for fault current limitation in the UK's power system, and some of the technical implications of this change.
Blair, S.M. +11 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
International Journal of Distributed Sensor Networks, 2013 It is significant to improve fault tolerance and transmission reliability for improving the overall performance of wireless sensor networks. Related studies on this issue become the hotspot at present.
Hongbing Li +5 more
doaj +1 more source