Results 91 to 100 of about 435,309 (318)
Rough set based gas turbine fault isolation study [PDF]
, 2010 Gas path fault isolation is one of the key techniques in Engine Health Management systems. In order to accomplish gas path fault isolation successfully for a gas turbine engine, both an accurate off-design performance model and an effective fault ...
Wang, Lihui.
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Analysis of fault networks and conjugate systems
, 2013 Faults networks exist over a range of scales and are important for understanding the brittle deformation and fluid transport processes within the Earth’s crust.
Nixon, Casey William
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Towards Immune Inspired Fault Tolerance in Embedded Systems [PDF]
, 2002 The immune system is a remarkable natural system that is proving to be of great inspiration to computer scientists and engineers alike. This paper discusses the role that the immune system can play in the development of fault tolerant embedded systems ...
Timmis, Jon +3 more
core +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Software-based fault-tolerant routing algorithm in multidimensional networks [PDF]
, 2006 Massively parallel computing systems are being built with hundreds or thousands of components such as nodes, links, memories, and connectors. The failure of a component in such systems will not only reduce the computational power but also alter the ...
Ould-Khaoua, M. +11 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Assessing multi-version systems through fault Injection [PDF]
, 2001 Multi-version design (MVD) has been proposed as a method for increasing the dependability of critical systems beyond current levels. However, a major obstacle to large-scale commercial usage of this approach is the lack of quantitative characterizations ...
Townend, Paul Michael
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