Results 131 to 140 of about 435,309 (318)
International Journal of Electrical Power & Energy SystemsTo avoid the issue of blind reclosing in conventional flexible high voltage direct current (HVDC) grid, investigating an adaptive reclosing scheme capable of identifying fault nature and duration is essential.
Yue Dai +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Geometry, evolution and scaling of fault relay zones in 3D using detailed observations from outcrops and 3D seismic data [PDF]
, 2011 A new surface attribute was developed during the course of the thesis, which enables fault-related deformation – specifically, the apparent dip of mapped horizons measured in a direction perpendicular to the average strike of a fault array (here termed ...
Long, Jonathan James +1 more
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Incorporation of fault rock properties into production simulation models [PDF]
, 2005 This thesis has two aims. First, to investigate the importance of incorporating the multiphase flow properties of faults into production simulation models.
Al-Busafi, Bader
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Current–time characteristics of resistive superconducting fault current limiters
, 2012 Superconducting fault current limiters (SFCLs) may play an important role in power-dense electrical systems. Therefore, it is important to understand the dynamic characteristics of SFCLs.
Burt, Graeme +2 more
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Fault severity diagnosis of rolling element bearings based on kurtogram and envelope analysis
, 2014 Faults in rolling element bearing are among the main causes of breakdown in rotating machines. Vibration is an effective technique for machine condition monitoring.
Gu, Fengshou +6 more
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