Results 31 to 40 of about 474,869 (318)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
A Multi-Objective Hybrid Cloud Resource Scheduling Method Based on Deadline and Cost Constraints
We propose a task-oriented multi-objective scheduling method based on ant colony optimization (MOSACO) to optimize the finite pool of public and private computing resources in a hybrid cloud computing environment according to deadline and cost ...
Liyun Zuo +4 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
FTPipeHD: A Fault-Tolerant Pipeline-Parallel Distributed Training Framework for Heterogeneous Edge Devices [PDF]
Yuhao Chen +4 more
openalex +1 more source
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Prasetya, I.S.W.B., Swierstra, S.D.
openaire +4 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sliding window constrained fault-tolerant filtering of compressor vibration data
This paper presents a sliding window constrained fault-tolerant filtering method for sampling data in petrochemical instrumentation. The method requires the design of an appropriate sliding window width based on the time series, as well as the expansion ...
Shaolin Hu, Xianxi Chen, Guoxi Sun
doaj +1 more source
Evolution of a Fault-Controlled, Deep-Water Sub-Basin, Tabernas, SE Spain
The Neogene Tabernas Basin, SE Spain, provides important evidence at outcrop for the interplay between tectonic deformation of the sea floor, slope instability and turbidity current behaviour.
Lucie Baudouy +3 more
doaj +1 more source
Disturbance decoupled functional observers for fault estimation in nonlinear systems [PDF]
Sunjeev Venkateswaran, Costas Kravaris
openalex +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

