Results 61 to 70 of about 474,869 (318)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Strong coupling between a single-photon and a two-photon Fock state

Nature Communications
The realization of strong nonlinear coupling between single photons has been a long-standing goal in quantum optics and quantum information science, promising wide impact applications, such as all-optical deterministic quantum logic and single-photon ...
Shuai-Peng Wang, Alberto Mercurio, Alessandro Ridolfo, Yuqing Wang, Mo Chen, Wenyan Wang, Yulong Liu, Huanying Sun, Tiefu Li, Franco Nori, Salvatore Savasta, J. Q. You   +11 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Estimation of inertia demand in power systems considering wind power virtual inertia

International Journal of Electrical Power & Energy Systems
The high proportion of renewable energy integrated into the grid through numerous power electronic devices has reduced the overall system inertia level and operational stability and caused poor disturbance resistance.
Hongchun SHU, Haifei DONG, Jing CHEN, Guangxue WANG, Xi WANG, Botao SHI   +5 more
doaj   +1 more source

A Rotor Coupling Fault Mechanism Modeling Based on the Deformation-Motion Vector Analysis Method [PDF]

, 2020
Hu Jun
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

When Mobile Crowd Sensing Meets Traditional Industry

IEEE Access, 2017
With the evolution of mobile phone sensing and wireless networking technologies, mobile crowd sensing (MCS) has become a promising paradigm for large-scale sensing applications. MCS is a type of multi-participant sensing that has been widely used by many
Lei Shu, Yuanfang Chen, Zhiqiang Huo, Neil Bergmann, Lei Wang   +4 more
doaj   +1 more source

Multiple Faults Estimation in Dynamical Systems: Tractable Design and Performance Bounds [PDF]

, 2020
Chris van der Ploeg, Mohsen Alirezaei, Nathan van de Wouw, Peyman Mohajerin Esfahani   +3 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source